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World J Gastroenterol. Nov 14, 2025; 31(42): 112478
Published online Nov 14, 2025. doi: 10.3748/wjg.v31.i42.112478
Published online Nov 14, 2025. doi: 10.3748/wjg.v31.i42.112478
Clinical predictors of multidrug-resistant Gram-negative pyogenic liver abscess and nomogram construction: A retrospective analysis
Ke Xu, Dong-Hui Wu, Chu-Jia Zeng, Jia-Yi Guo, Zhi-Yuan Yao, Graduate School, Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China
De-Yang Xi, Department of Intensive Care Unit, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China
Meng-Jiao Wang, Department of Gastroenterology, Beilun District People’s Hospital, Ningbo 315800, Zhejiang Province, China
An-Qiang Feng, Department of Digestive Disease, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China
Fang Ji, Xue-Bing Yan, Chun-Yang Li, Department of Infectious Diseases, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221132, Jiangsu Province, China
Li-Li Ye, Department of Pediatrics, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China
Co-first authors: Ke Xu and Dong-Hui Wu.
Co-corresponding authors: Li-Li Ye and Chun-Yang Li.
Author contributions: Xu K and Wu DH share co-first authorship based on their equivalent substantive contributions to experimental execution and analytical rigor throughout this collaborative research; Li CY and Xu K contributed to the study design; Xu K conducted literature screening, quality assessment, and manuscript drafting; Xu K, Wu DH, and Zeng CJ performed statistical analyses; Guo JY executed literature mining; Wu DH, Xi DY, Wang MJ, Yao ZY, Feng AQ, and Ye LL conducted data analysis; Li CY, Yan XB, and Ye LL edited manuscript; Ji F provided conceptual guidance and secured funding; Li CY and Ye LL share co-corresponding authorship for their joint leadership in research coordination, intellectual direction, and conceptual innovation, reflecting the project’s collaborative ethos. All authors reviewed and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of The Affiliated Hospital of Xuzhou Medical University, No. XYFY2025-KL262-01.
Informed consent statement: Due to the retrospective and observational nature of the study without active interventions, the institutional review board waived the necessity of obtaining individual informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author. Participants gave informed consent for data sharing.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Yang Li, PhD, Chief Physician, Department of Infectious Diseases, The Affiliated Hospital of Xuzhou Medical University, No. 9 Kunpeng North Road, Economic and Technological Development Zone, Xuzhou 221132, Jiangsu Province, China. lichunyangyelili@126.com
Received: July 29, 2025
Revised: August 19, 2025
Accepted: October 14, 2025
Published online: November 14, 2025
Processing time: 108 Days and 1.5 Hours
Revised: August 19, 2025
Accepted: October 14, 2025
Published online: November 14, 2025
Processing time: 108 Days and 1.5 Hours
Core Tip
Core Tip: This study identifies age ≥ 60, diabetes, malignant tumor, lower C-reactive protein levels, and prolonged prothrom