Early risk stratification of post-endoscopic retrograde cholangiopancreatography pancreatitis using 4-hour serum amylase and lipase: A prospective study
Jang Han Jung, Kyong Joo Lee, Se Woo Park, Da Hae Park, Hye Won Cha, Dong Hee Koh, Jin Lee
Jang Han Jung, Kyong Joo Lee, Se Woo Park, Da Hae Park, Hye Won Cha, Dong Hee Koh, Jin Lee, Division of Gastroenterology, Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong 18450, Gyeonggi, South Korea
Co-first authors: Jang Han Jung and Kyong Joo Lee.
Author contributions: Jung JH, Lee KJ, and Park SW wrote the manuscript; Jung JH, Lee KJ, Park SW, Park DH, Cha HW, Koh DH, and Lee J analyzed and interpreted the data; Park SW designed the study, collected the data, and performed the statistical analysis. All authors approved the final manuscript.
Supported by National Research Foundation of Korea, No. NFR-2022R1C1C1006242; and the Hallym University Medical Center Research Fund.
Institutional review board statement: The study adhered to the ethical guidelines of the Declaration of Helsinki and was approved by the Institutional Review Board of Hallym University Dongtan Sacred Hospital (Approval No. 2020-10-001-001).
Clinical trial registration statement: This trial was registered in the International Clinical Trials Registry Platform (
https://cris.nih.go.kr) under registration No. KCT0005950.
Informed consent statement: Informed consent was obtained from all patients prior to the procedure.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: The data that support the findings of this study are not publicly available, as they are proprietary to the corresponding author; however, detailed summaries and analyses are provided within the article and its
Supplementary materials.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Se Woo Park, MD, PhD, Professor, Division of Gastroenterology, Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, 7 Keunjaebong-gil, Hwaseong 18450, Gyeonggi, South Korea.
mdsewoopark@gmail.com
Received: June 27, 2025
Revised: July 18, 2025
Accepted: September 11, 2025
Published online: October 21, 2025
Processing time: 117 Days and 7.4 Hours
