Rate of abnormal renal function index and related risk factors in patients with chronic hepatitis B

doi:10.3748/wjg.v31.i25.105207

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 31, Issue 25

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (43)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series, Tables (1-7) series.

Item

Count

PDF

HTML

Figures (1-1)

Tables (1-7)

Sum=40

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=0

Jul 7, 2025 (publication date) through Jul 4, 2025

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Jul 7, 2025; 31(25): 105207
Published online Jul 7, 2025. doi: 10.3748/wjg.v31.i25.105207

Rate of abnormal renal function index and related risk factors in patients with chronic hepatitis B

Guo-Feng Gao, Xiao-Yu Wang, Jiao Yu

Guo-Feng Gao, Xiao-Yu Wang, Jiao Yu, Department of Hepatology, Shanghai Eastern Hepatobiliary Surgery Hospital, Navy Medical University, Shanghai 200433, China

Author contributions: Yu J designed and conducted the study; Gao GF contributed to the analysis and wrote the paper; Wang XY collected the data; All authors have read and approved the final manuscript.

Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Shanghai Eastern Hepatobiliary Surgery Hospital (Approval No. EHBHKY2022-H006-P001).

Informed consent statement: The study protocol was in accordance with the ethical guidelines of the 1975 Declaration of Helsinki. All patients provided informed written consent prior to study enrollment.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Data sharing statement: Datasets are available from the corresponding author at yujiao7828@sina.com.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Jiao Yu, Chief, MD, PhD, Department of Hepatology, Shanghai Eastern Hepatobiliary Surgery Hospital, Navy Medical University, No. 700 Moyu North Road, Jiading District, Shanghai 200433, China. yujiao7828@sina.com

Received: February 18, 2025
Revised: March 20, 2025
Accepted: May 8, 2025
Published online: July 7, 2025
Processing time: 136 Days and 1.2 Hours

Core Tip

Core Tip: Oral nucleos(t)ide analogues have been widely used for the treatment of chronic hepatitis B; however, their effects on kidney function remain inconclusive. In this study, no statistically significant differences in the effects of different antiviral drugs on renal function were observed. Urinary β2-microglobulin did not have a significant advantage over estimated glomerular filtration rate as an early warning of renal dysfunction. In addition, being male was an independent risk factor for renal impairment. Thus, men should pay more attention to the changes in renal function indicators when using antiviral drugs, which can provide a clear direction for clinical medication.