Utilization of molecular genetic approaches for colorectal cancer screening

doi:10.3748/wjg.v30.i46.4950

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Dec 14, 2024 (publication date) through Nov 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2024; 30(46): 4950-4957
Published online Dec 14, 2024. doi: 10.3748/wjg.v30.i46.4950

Utilization of molecular genetic approaches for colorectal cancer screening

Marina A Emelyanova, Anna Y Ikonnikova

Marina A Emelyanova, Anna Y Ikonnikova, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia

Author contributions: Emelyanova MA and Ikonnikova AY wrote and revised the manuscript; and all authors have read and approved the final manuscript.

Supported by the Ministry of Science and Higher Education of the Russian Federation to the EIMB Center for Precision Genome Editing and Genetic Technologies for Biomedicine Under the Federal Research Program for Genetic Technologies Development for 2019-2027, No. 075-15-2019-1660.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Marina A Emelyanova, PhD, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, No. 32 Vavilov Street, Moscow 119991, Russia. emel_marina@eimb.ru

Received: July 22, 2024
Revised: October 14, 2024
Accepted: November 1, 2024
Published online: December 14, 2024
Processing time: 121 Days and 21 Hours

Core Tip

Core Tip: Despite the significant benefits of colorectal cancer (CRC) screening, current approaches need improvement. Here, we focus on molecular genetic techniques that may be useful in CRC screening. Their improvement and implementation are promising, on the one hand, due to their non-invasive nature, which enhances patient adherence to screening, and on the other hand, due to the personalization of screening programs based on an assessment of the individual risk of developing CRC.