Optimization of colorectal cancer screening strategies: New insights

Core Tip

Core Tip: Despite the proven mortality benefits, adherence to colorectal cancer (CRC) screening guidelines remains low in many regions worldwide. Because nation-wide screening is not feasible due to limited financial and human resources, it is crucial to identify high-risk groups that ought to participate in screening measures. However, variation in each population is to be considered when implementing screening procedures, and barriers affecting adherence to screening guidelines should be addressed in each specific population. Finally, patients with comorbidities who regularly schedule visits to the hospital are diagnosed at an early stage similar to those who undergo periodic screening. This underscores the importance of encouraging patients with comorbidities who do not attend routine visits to undergo screening to reduce the burden of late-stage CRC diagnosis.