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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2023; 29(30): 4616-4627
Published online Aug 14, 2023. doi: 10.3748/wjg.v29.i30.4616
Published online Aug 14, 2023. doi: 10.3748/wjg.v29.i30.4616
Helicobacter pylori intragastric colonization and migration: Endoscopic manifestations and potential mechanisms
Tong Mu, Wen-Wen Wang, Hua Feng, Qian Ding, Li-Fen Wang, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Zhi-Ming Lu, Yan Jin, Department of Clinical Laboratory Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Author contributions: Mu T drafted the article; Lu ZM and Jin Y made contributions to the design of the article; Wang WW, Feng H and Ding Q revised the article; Wang LF provides figures, revised the article and made the decision to submit for publication; all authors have read and approved the final manuscript.
Supported by Medical Health Science and Technology Development Plan Project of Shandong Province , No. 202103030765 ; and Natural Science Foundation of Shandong Province , No. ZR2021QH195 and No. ZR2020QH035 .
Conflict-of-interest statement: All authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Fen Wang, MD, Associate Chief Physician, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 9677 Jing Shi Road, Jinan 250021, Shandong Province, China.
Received: May 9, 2023
Peer-review started: May 9, 2023
First decision: June 14, 2023
Revised: July 1, 2023
Accepted: July 25, 2023
Article in press: July 25, 2023
Published online: August 14, 2023
Processing time: 92 Days and 22.3 Hours
Peer-review started: May 9, 2023
First decision: June 14, 2023
Revised: July 1, 2023
Accepted: July 25, 2023
Article in press: July 25, 2023
Published online: August 14, 2023
Processing time: 92 Days and 22.3 Hours
Core Tip
Core Tip:Helicobacter pylori (H. pylori) adopts several effective strategies to adhere to and colonize the gastric mucosa and move to different regions of the stomach, leading to acute infection and chronic gastritis that can be observed through endoscopy. Herein, we describe the endoscopic manifestations of each stage of H. pylori gastritis and then discuss the potential mechanisms of bacterial intragastric colonization and migration from the perspective of endoscopists to provide direction for future research on the effective therapy and management of H. pylori infection.