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World J Gastroenterol. Jul 7, 2023; 29(25): 4021-4035
Published online Jul 7, 2023. doi: 10.3748/wjg.v29.i25.4021
Dynamic contrast enhanced ultrasound in gastrointestinal diseases: A current trend or an indispensable tool?
Mattia Paratore, Matteo Garcovich, Maria Elena Ainora, Laura Riccardi, Antonio Gasbarrini, Maria Assunta Zocco
Mattia Paratore, Matteo Garcovich, Maria Elena Ainora, Laura Riccardi, Medicina Interna e Gastroenterologia, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome 00168, Italy
Antonio Gasbarrini, Maria Assunta Zocco, Medicina Interna e Gastroenterologia, CEMAD Digestive Disease Center, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome 00168, Italy
Author contributions: Paratore M, Garcovich M and Zocco MA contributed to conceptualization, review of the literature and collection of data, writing first draft, review and editing; Ainora ME, Riccardi L and Gasbarrini A contributed to conceptualization, supervision, review, and editing; all authors revised the manuscript critically for intellectual content and have approved the final version.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Matteo Garcovich, MD, PhD, Research Scientist, Staff Physician, Medicina Interna e Gastroenterologia, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, Rome 00168, Italy. matteogarcovich@yahoo.it
Received: March 26, 2023
Peer-review started: March 26, 2023
First decision: May 13, 2023
Revised: May 24, 2023
Accepted: June 5, 2023
Article in press: June 5, 2023
Published online: July 7, 2023
Processing time: 93 Days and 21.8 Hours
Core Tip

Core Tip: Contrast-enhanced ultrasound (CEUS) has been widely implemented in clinical practice in recent years. Despite its several advantages, the qualitative evaluation of this exam and the lack of objectivity could lead to variability between different operators and ultrasound equipments. Dynamic-CEUS (D-CEUS) with the measurement of perfusion parameters is aimed at overcoming this important limitation. The purpose of this review is to explore the usefulness of D-CEUS in gastroenterological diseases.