©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2022; 28(11): 1184-1186
Published online Mar 21, 2022. doi: 10.3748/wjg.v28.i11.1184
Published online Mar 21, 2022. doi: 10.3748/wjg.v28.i11.1184
New treatment for gastroesophageal reflux disease: Traditional Chinese medicine Xiaochaihu decoction
Li-Ying Xu, Department of Emergency Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China
Bin-Yan Yu, Department of Acupuncture and Moxibustion, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China
Lu-Sha Cen, Department of Ophthalmology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China
Author contributions: Xu LY and Cen LS designed the research; Yu BY analyzed the data; Xu LY and Cen LS performed the research and wrote the letter; Cen LS revised the letter.
Supported by Scientific Research Project of Zhejiang TCM Science and Technology Programme , No. 2020ZB067, No. 2020ZT001, and No. 2021ZQ031; and National Natural Science Foundation of China , No. 81503522 and No. 82104862 .
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Corresponding author: Lu-Sha Cen, PhD, Attending Doctor, Department of Ophthalmology, The First Affiliated Hospital of Zhejiang Chinese Medical University, No. 54 Youdian Road, Hangzhou 310006, Zhejiang Province, China. cenlusa2@sina.com
Received: August 26, 2021
Peer-review started: August 26, 2021
First decision: September 4, 2021
Revised: September 17, 2021
Accepted: February 23, 2022
Article in press: February 23, 2022
Published online: March 21, 2022
Processing time: 203 Days and 0.8 Hours
Peer-review started: August 26, 2021
First decision: September 4, 2021
Revised: September 17, 2021
Accepted: February 23, 2022
Article in press: February 23, 2022
Published online: March 21, 2022
Processing time: 203 Days and 0.8 Hours
Core Tip
Core Tip: Modified Xiaochaihu decoction (MXD) has been applied for gastroesophageal reflux disease (GRED) for thousands of years in Asian countries. Li et al proved that MXD is an ideal optional therapy for GERD. The drug selection of herbal granule makes double-blind research achievable. Side effects of MXD should be noted. As a chronic disease, GERD rehabilitation requires prolonged observation of the clinical course with MXD therapy.