Clinical Trials Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 21, 2020; 26(43): 6867-6879
Published online Nov 21, 2020. doi: 10.3748/wjg.v26.i43.6867
Comparison of two supplemental oxygen methods during gastroscopy with propofol mono-sedation in patients with a normal body mass index
Liu-Jia-Zi Shao, Yi Zou, Fu-Kun Liu, Lei Wan, Shao-Hua Liu, Fang-Xiao Hong, Fu-Shan Xue
Liu-Jia-Zi Shao, Yi Zou, Fu-Kun Liu, Lei Wan, Shao-Hua Liu, Fang-Xiao Hong, Fu-Shan Xue, Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Author contributions: Shao LJZ and Zou Y contributed equally to this study, study design/planning, study conduct, data analysis, and writing and revising the paper; Liu FK assisted with study conduct, data analysis, and revising the paper; Wan L assisted with study design/planning, study conduct, data analysis, and revising the paper; Liu SH assisted with study conduct, data analysis and curation, and revising the paper; Hong FX assisted with study design/planning, study conduct, data analysis, and revising the paper; Xue FS assisted with study design/planning, study conduct, and writing and revising the paper.
Supported by “Renfu” Research Fund by Chinese Society of Digestive Endoscopy, No. CSDE012017120006.
Institutional review board statement: This study was approved by the Institutional Ethics Committee of Beijing Friendship Hospital, China (Ethics Committee number: 2017-P2-009-02).
Clinical trial registration statement: This study is registered with the Chinese Clinical Trial Registry (registration No. ChiCTR-IOR-17013089).
Informed consent statement: The written informed consent was obtained from each patient included in the study.
Conflict-of-interest statement: No external funding or competing interests declared.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fu-Shan Xue, MD, Professor, Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong’an Road, Xicheng District, Beijing 100050, China. fushanxue@outlook.com
Received: July 19, 2020
Peer-review started: July 19, 2020
First decision: August 8, 2020
Revised: August 10, 2020
Accepted: October 20, 2020
Article in press: October 20, 2020
Published online: November 21, 2020
Processing time: 121 Days and 20.3 Hours
Core Tip

Core Tip: This study is a prospective randomized controlled trial aimed to determine whether the Wei nasal jet tube (WNJT) performs better than the nasal prongs for the prevention of hypoxemia during gastroscopy with propofol mono-sedation when a moderate oxygen flow is provided in patients with a normal body mass index. Our results show that compared with nasal prongs for supplemental oxygen, the WNJT is more effective for the prevention of hypoxemia during gastroscopy with propofol mono-sedation when a moderate oxygen flow is provided. However, the WNJT caused slight epistaxis in a few patients.