Gao CC, Li J, Cao F, Wang XH, Li A, Wang Z, Li F. Infection recurrence following minimally invasive treatment in patients with infectious pancreatic necrosis. World J Gastroenterol 2020; 26(22): 3087-3097 [PMID: 32587450 DOI: 10.3748/wjg.v26.i22.3087]
Corresponding Author of This Article
Fei Li MD, PhD, Chief Doctor, Professor, Surgeon, Department of General Surgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China. feili36@ccmu.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
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Gao CC, Li J, Cao F, Wang XH, Li A, Wang Z, Li F. Infection recurrence following minimally invasive treatment in patients with infectious pancreatic necrosis. World J Gastroenterol 2020; 26(22): 3087-3097 [PMID: 32587450 DOI: 10.3748/wjg.v26.i22.3087]
World J Gastroenterol. Jun 14, 2020; 26(22): 3087-3097 Published online Jun 14, 2020. doi: 10.3748/wjg.v26.i22.3087
Infection recurrence following minimally invasive treatment in patients with infectious pancreatic necrosis
Chong-Chong Gao, Jia Li, Feng Cao, Xiao-Hui Wang, Ang Li, Zhe Wang, Fei Li
Chong-Chong Gao, Jia Li, Feng Cao, Xiao-Hui Wang, Ang Li, Zhe Wang, Fei Li, Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
Author contributions: Gao CC designed and performed the research and wrote the paper; Li F designed the research and supervised the report; Cao F, Wang XH, and Li J designed the research and contributed to the analysis; Li A and Wang Z provided clinical advice.
Supported byBeijing Municipal Science and Technology Commission, No. Z171100001017077; Beijing Municipal Administration of Hospitals Clinical Medicine Development of special funding support, No. XMLX201404; and Construction Project of Advanced Clinical Medicine Discipline of Capital Medical University, No. 1192070312.
Institutional review board statement: The study was reviewed approved by the ethics committee of Xuanwu Hospital.
Informed consent statement: Due to the nature of retrospective study, written informed consents were waived.
Conflict-of-interest statement: All other authors have nothing to disclose.
Data sharing statement: The original anonymous dataset is available on request from the corresponding author at feili36@ccmu.edu.cn.
Corresponding author: Fei Li MD, PhD, Chief Doctor, Professor, Surgeon, Department of General Surgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China. feili36@ccmu.edu.cn
Received: January 2, 2020 Peer-review started: January 2, 2020 First decision: February 19, 2020 Revised: February 23, 2020 Accepted: May 13, 2020 Article in press: May 13, 2020 Published online: June 14, 2020 Processing time: 163 Days and 23.7 Hours
Core Tip
Core tip: This retrospective study investigated infection recurrence following successful minimally invasive treatment in infected pancreatic necrosis (IPN) patients. Our data demonstrated that infection recurred in 7.30% of IPN patients after drainage catheter removal. This can be predicted by white blood cell count, serum C-reactive protein, and procalcitonin levels measured at the time of catheter removal, and length of the catheter measured by computerized tomography scan. In particular, white blood cell count and serum procalcitonin level were highly sensitive and specific for predicting infection recurrence. These factors should be considered before removing the drainage catheters following minimally invasive treatment in IPN patients.
