©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 21, 2018; 24(39): 4428-4435
Published online Oct 21, 2018. doi: 10.3748/wjg.v24.i39.4428
Published online Oct 21, 2018. doi: 10.3748/wjg.v24.i39.4428
Novel targeting approaches and signaling pathways of colorectal cancer: An insight
Ankita Tiwari, Shivani Saraf, Amit Verma, Pritish Kumar Panda, Sanjay K Jain, Pharmaceutics Research Projects Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour Central University, Sagar 470003, India
Author contributions: Tiwari A drafted the manuscript after searching appropriate literature; Panda PK contributed in the writing work; Saraf S and Verma A contributed the related figures; Jain SK critically interpreted the findings of other scientists and revised the final version of the manuscript.
Conflict-of-interest statement: No conflict of interest exists.
Correspondence to: Sanjay K Jain, PhD, Full Professor, Pharmaceutics Research Projects Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour Central University, Sagar 470003, India. drskjainin@yahoo.com
Telephone: +91-7582-265457 Fax: +91-7582-264236
Received: July 10, 2018
Peer-review started: July 10, 2018
First decision: July 18, 2018
Revised: August 24, 2018
Accepted: October 5, 2018
Article in press: October 5, 2018
Published online: October 21, 2018
Processing time: 100 Days and 2.9 Hours
Peer-review started: July 10, 2018
First decision: July 18, 2018
Revised: August 24, 2018
Accepted: October 5, 2018
Article in press: October 5, 2018
Published online: October 21, 2018
Processing time: 100 Days and 2.9 Hours
Core Tip
Core tip: In spite of the advancements in the diagnosis and the treatment approaches for colorectal cancer (CRC), its survival rate is quite low. Therefore, there arises an urge to develop novel targeting strategies for its effective treatment. A meticulous apprehension of the signaling cascade is necessitated for better outcomes. In a nutshell, this editorial highlights various novel targeting approaches like gene therapy and immunotherapy which could usher better targeting of CRC.