Colorectal cancer screening: An updated review of the available options

Core Tip

Core tip: Multiple societies have published screening guidelines concerning colorectal cancer (CRC) screening. Despite that, global participation can be challenging due to wide variability in the availability of screening tools, especially the newer resources. Additionally, patient friendly approach, improving patient uptake, adherence, and compliance to attain national CRC screening goals are still lacking. Regardless of the screening approaches utilized, it is necessary to demonstrate high sensitivity for detection of advanced neoplasia and CRC, as well as high specificity for costeffectiveness. Furthermore, they must have broad acceptability to the general population, healthcare providers, and third-party payers. Hence, achieving most of the screening value that is derived from cancer prevention over cancer detection. Recently, a very appealing blood test was FDA approved for screening, this modality certainly carries significant appeal, but how does it fare when we compare to the rest of tests? This is the question we aim to answer through this review.