Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 14, 2016; 22(42): 9419-9426
Published online Nov 14, 2016. doi: 10.3748/wjg.v22.i42.9419
Full-thickness myotomy is associated with higher rate of postoperative gastroesophageal reflux disease
Xue-Hong Wang, Yu-Yong Tan, Hong-Yi Zhu, Chen-Jie Li, De-Liang Liu
Xue-Hong Wang, Yu-Yong Tan, Hong-Yi Zhu, Chen-Jie Li, De-Liang Liu, Department of Gastroenterology, the Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China
Author contributions: Wang XH and Liu DL designed the study; Tan YY, Zhu HY and Li CJ acquired the clinical data; Wang XH and Liu DL analyzed the data; Wang XH, Tan YY and Liu DL wrote and revised the paper.
Supported by the Development and Reform Commission of Hunan Province, China, No. XFGTZ2014713.
Institutional review board statement: The study was approved by the Ethics Committee of the Second Xiangya Hospital of Central South University, Changsha, China.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There was no potential conflict of interest related to this study.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: De-Liang Liu, MD, Professor, Director, Department of Gastroenterology, the Second Xiangya Hospital of Central South University, NO.139 Middle Renmin Road, Changsha 410011, Hunan Province, China. liudeliang@medmail.com.cn
Telephone: +86-731-85295035 Fax: +86-731-85295888
Received: June 22, 2016
Peer-review started: June 22, 2016
First decision: August 29, 2016
Revised: September 12, 2016
Accepted: October 10, 2016
Article in press: October 10, 2016
Published online: November 14, 2016
Processing time: 143 Days and 12.6 Hours
Core Tip

Core tip: Gastroesophageal reflux disease (GERD) is a major concern following peroral endoscopic myotomy for achalasia. Although short-term follow-up did not show an increased rate of GERD in patients who received full-thickness myotomy compared with circular myotomy, the long-term difference is still unknown. We found that full-thickness myotomy is associated with a higher rate of clinically relevant GERD.