©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 28, 2016; 22(4): 1551-1569
Published online Jan 28, 2016. doi: 10.3748/wjg.v22.i4.1551
Published online Jan 28, 2016. doi: 10.3748/wjg.v22.i4.1551
Post reperfusion syndrome during liver transplantation: From pathophysiology to therapy and preventive strategies
Antonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Laura Lorenzini, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy
Giorgio Ercolani, Division of Surgery, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy
Author contributions: Siniscalchi A, Gamberini L, Laici C, Bardi T, Ercolani G, Lorenzini L and Faenza S solely contributed to this manuscript.
Supported by The Department of Anesthesiology of the University of Bologna.
Conflict-of-interest statement: The authors of this review certify that they have no affiliations with, or involvement in any organization or entity with any financial or non-financial interest, relating to the subject matter or the materials discussed in this manuscript.
Correspondence to: Antonio Siniscalchi, MD, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. sinianest@libero.it
Telephone: +39-51-6363440
Received: April 17, 2015
Peer-review started: April 19, 2015
First decision: October 14, 2015
Revised: October 20, 2015
Accepted: November 9, 2015
Article in press: November 9, 2015
Published online: January 28, 2016
Processing time: 277 Days and 21.1 Hours
Peer-review started: April 19, 2015
First decision: October 14, 2015
Revised: October 20, 2015
Accepted: November 9, 2015
Article in press: November 9, 2015
Published online: January 28, 2016
Processing time: 277 Days and 21.1 Hours
Core Tip
Core tip: Post reperfusion syndrome (PRS) is a serious intraoperative complication of liver transplantation that can influence recipient’s morbidity and mortality. This review provides a description of the evolution throughout the years of the concept of PRS, and gathers the existing evidence regarding the pathophysiologic mechanisms involved and the possible management and preventive strategies.