Ying Ding, Sheng-Xiang Rao, Cai-Zhong Chen, Ren-Chen Li, Meng-Su Zeng, Department of Radiology, Zhongshan Hospital of Fudan University, Shanghai Institute of Medical Imaging, Shanghai 200032, China
Author contributions: Rao SX and Zeng MS designed the study; Ding Y and Chen CZ performed the research; Li RC and Rao SX analyzed the data; Ding Y wrote the paper; and Ding Y revised the manuscript for final submission.
Supported by National Natural Science Foundation of China, No. 81371543.
Ethics approval: The study was reviewed and approved by the Zhongshan Hospital Fudan University Institutional Review Board.
Clinical trial registration: This study is registered at Zhongshan Hospital Fudan University. The registration identification number is 2010-17.
Informed consent: The requirement for informed consent was waived for our study.
Conflict-of-interest: No potential conflicts of interest relevant to this article are reported.
Data sharing: No additional data are available.
Correspondence to: Sheng-Xiang Rao, MD, PhD, Department of Radiology, Zhongshan Hospital of Fudan University, Shanghai Institution of Medical Imaging, 180 Fenglin Road, Xuhui District, Shanghai 200032, China. raoxray@126.com
Telephone: +86-21-64041990 Fax: +86-21-64041990
Received: November 9, 2014 Peer-review started: November 10, 2014 First decision: December 11, 2014 Revised: December 22, 2014 Accepted: February 5, 2015 Article in press: February 5, 2015 Published online: April 28, 2015 Processing time: 168 Days and 21.2 Hours
Core Tip
Core tip: The role of three dimensional gradient echo sequence with volumetric interpolated breath-hold examination (VIBE) by using chemically selective fat-saturation for abdominal magnetic resonance (MR) imaging is well established and it is now part of the standard clinical work-up, especially for dynamic contrast-enhanced liver MR imaging. The Dixon technique has been improved extensively in the aspects of phase errors, noise and artifacts. There are no reports yet on the potential value of two-point Dixon fat-water separation technique for image quality and focal liver lesions in hepatobiliary phase of gadoxetic acid-enhanced MR imaging. Therefore, we compare the image quality and liver-to-lesion contrast in hapatobiliary phase between VIBE using two-point Dixon fat-water separation and chemically selective fat saturation.
