Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2015; 21(12): 3746-3749
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3746
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3746
Cetuximab and panitumumab in a patient with colon cancer and concomitant chronic skin disease: A potential beneficial effect on psoriasis vulgaris
Ken Okamoto, Michiya Kobayashi, Department of Human Health and Medical Sciences, Kochi Medical School Hospital, Kochi 783-8505, Japan
Hiromichi Maeda, Cancer Treatment Center, Kochi Medical School Hospital, Kochi 783-8505, Japan
Takeo Shiga, Department of Dermatology, Kochi Medical School, Kochi 783-8505, Japan
Mai Shiga, Ken Dabanaka, Kazuhiro Hanazaki, Department of Surgery, Kochi Medical School, Kochi 783-8505, Japan
Author contributions: Okamoto K, Hanazaki K and Kobayashi M designed the report; Okamoto K, Shiga T, Shiga M and Dabanaka K were attending doctors for the patients and performed surgical operation; Okamoto K and Maeda H wrote the manuscript.
Ethics approval: Kochi Medical School Institutional Review Board (IRB) reviewed this study, and judged that there is no necessity to discuss this study (case report) in IRB.
Informed consent: The patient provided written informed consent for this case report.
Conflict-of-interest: There is no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Ken Okamoto, Department of Human Health and Medical Sciences, Kochi Medical School Hospital, Kohasu, Oko-cho, Nankoku-city, Kochi 783-8505, Japan. okamoto@kochi-u.ac.jp
Telephone: +81-88-8802182 Fax: +81-88-8802183
Received: October 6, 2014
Peer-review started: October 6, 2014
First decision: October 29, 2014
Revised: November 12, 2014
Accepted: December 19, 2014
Article in press: December 22, 2014
Published online: March 28, 2015
Processing time: 175 Days and 4.8 Hours
Peer-review started: October 6, 2014
First decision: October 29, 2014
Revised: November 12, 2014
Accepted: December 19, 2014
Article in press: December 22, 2014
Published online: March 28, 2015
Processing time: 175 Days and 4.8 Hours
Core Tip
Core tip: Anti- epidermal growth factor receptor (EGFR) antibodies are effective in treating advanced colorectal cancer. However, anti-EGFR antibodies are not generally used in patients with concomitant chronic skin disease due to dermatological toxicities. In this case report, we present a patient with psoriasis vulgaris whose symptoms lessened during treatment with anti-EGFR antibody monotherapy for metastatic colon cancer. Based on this result, we consider that patients with concomitant skin disease should still be considered for anti-EGFR antibody therapy.