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World J Gastroenterol. Jan 7, 2014; 20(1): 303-309
Published online Jan 7, 2014. doi: 10.3748/wjg.v20.i1.303
Published online Jan 7, 2014. doi: 10.3748/wjg.v20.i1.303
Controlled low central venous pressure reduces blood loss and transfusion requirements in hepatectomy
Zhi Li, Yu-Ming Sun, Fei-Xiang Wu, Li-Qun Yang, Zhi-Jie Lu, Wei-Feng Yu, Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200438, China
Author contributions: Li Z and Sun YM contributed equally to this study; Yu WF and Li Z designed the study and wrote the manuscript; Li Z and Sun YM performed the majority of analyses; Li Z, Wu FX, Yang LQ and Lu ZJ were also involved in revising the manuscript.
Correspondence to: Wei-Feng Yu, MD, Professor, Department of Anaesthesiology, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, No. 225, Changhai Road, Shanghai 200438, China. ywf808@sohu.com
Telephone: +86-21-81875231 Fax: +86-21-81875231
Received: August 18, 2013
Revised: October 7, 2013
Accepted: November 1, 2013
Published online: January 7, 2014
Processing time: 154 Days and 20.8 Hours
Revised: October 7, 2013
Accepted: November 1, 2013
Published online: January 7, 2014
Processing time: 154 Days and 20.8 Hours
Core Tip
Core tip: The morbidity and mortality after hepatic resection have been reported to correlate with excessive intraoperative blood loss and blood transfusion. This meta-analysis showed that controlled low central venous pressure is a simple and effective technique to reduce blood loss and blood transfusion during liver resection, and appears to have no detrimental effects on liver and renal function.