Letters To The Editor
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World J Gastroenterol. Nov 28, 2013; 19(44): 8160-8162
Published online Nov 28, 2013. doi: 10.3748/wjg.v19.i44.8160
Hydroxycitric acid does not promote inflammation or liver toxicity
Dallas L Clouatre, Harry G Preuss
Dallas L Clouatre, Glykon Technologies Group, LLC, Seattle, WA 98109, United States
Harry G Preuss, Department of Physiology, Georgetown University Medical Center, Washington, DC 20057, United States
Author contributions: Clouatre DL developed the primary draft collaborating; Preuss HG worked on data interpretation and analysis; both authors worked on the revisions and approved the version submitted.
Correspondence to: Dallas L Clouatre, PhD, Glykon Technologies Group, LLC, 24 Roy Street No. 401, Seattle, WA 98109, United States. dallasclouatre@mac.com
Telephone: +1-510-2894331 Fax: +1-206-9253568
Received: August 15, 2013
Revised: September 12, 2013
Accepted: September 15, 2013
Published online: November 28, 2013
Processing time: 118 Days and 5 Hours
Core Tip

Core tip: The preponderance of animal and human studies of Garcinia cambogia extract have found it to reduce markers of inflammation in brain, intestines, kidney and serum and to be either protective or neutral in terms of liver health. The limited reports of toxicities thus far have been linked to improperly manufactured materials and/or to peculiarities with the animal models used. The available data indicate that Garcinia cambogia extract/hydroxycitric acid does not cause liver toxicity.