Xiong JJ, Nunes QM, Huang W, Tan CL, Ke NW, Xie SM, Ran X, Zhang H, Chen YH, Liu XB. Laparoscopic vs open total gastrectomy for gastric cancer: A meta-analysis. World J Gastroenterol 2013; 19(44): 8114-8132 [PMID: 24307808 DOI: 10.3748/wjg.v19.i44.8114]
Corresponding Author of This Article
Xu-Bao Liu, MD, PhD, Professor, Department of Hepato-Biliary-Pancreatic Surgery, West China Hospital, Sichuan University, Guo Xue Rd 37, Chengdu 610041, Sichuan Province, China. liuxb2011@126.com
Research Domain of This Article
Surgery
Article-Type of This Article
Meta-Analysis
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jun-Jie Xiong, Chun-Lu Tan, Neng-Wen Ke, Si-Ming Xie, Xun Ran, Hao Zhang, Yong-Hua Chen, Xu-Bao Liu, Department of Hepato-Biliary-Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Quentin M Nunes, Wei Huang, NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool L69 3GA, United Kingdom
Author contributions: Xiong JJ and Nunes QM contributed equally to this work; Liu XB, Chen YH and Zhang H designed the research, and corrected and approved the manuscript; Xiong JJ, Nunes QM and Tan CL developed the literature search and carried out the statistical analyses of the studies; Huang W, Ke NW, Xie SM and Ran X performed data extraction; Xiong JJ, Nunes QM and Huang W wrote the manuscript; All authors read and approved the final manuscript.
Supported by UK/China Postgraduate Scholarships for Excellence, an NIHR Translational Research Fellowship and a Royal College of Surgeons of England-Ethicon Research Fellowship grant
Correspondence to: Xu-Bao Liu, MD, PhD, Professor, Department of Hepato-Biliary-Pancreatic Surgery, West China Hospital, Sichuan University, Guo Xue Rd 37, Chengdu 610041, Sichuan Province, China. liuxb2011@126.com
Telephone: +86-28-85422474 Fax: +86-28-85422872
Received: June 19, 2013 Revised: September 10, 2013 Accepted: September 16, 2013 Published online: November 28, 2013 Processing time: 175 Days and 4.2 Hours
Core Tip
Core tip: Currently, surgical resection is the mainstay treatment for gastric cancer. With technical advances and improved instrumentation, laparoscopic total gastrectomy (LTG) is being used increasingly to treat this malignant disease. However, compared with conventional open total gastrectomy (OTG), the safety and technical feasibility of LTG have not been adequately evaluated. This study clarified that, compared with OTG, LTG has similar short-term oncological outcomes, analgesic use and mortality. Furthermore, LTG was associated with lower intraoperative blood loss and overall complication rate, fewer wound-related complications, quicker recovery of gastrointestinal motility and a shorter hospital stay, albeit with a longer operation time.
