Brief Article
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World J Gastroenterol. Sep 14, 2013; 19(34): 5678-5684
Published online Sep 14, 2013. doi: 10.3748/wjg.v19.i34.5678
Fatty acids of erythrocyte membrane in acute pancreatitis patients
Irma Kuliaviene, Antanas Gulbinas, Johannes Cremers, Juozas Pundzius, Limas Kupcinskas, Zilvinas Dambrauskas, Eugene Jansen
Irma Kuliaviene, Limas Kupcinskas, Department of Gastroenterology, Medical Academy, Lithuanian University of Health Sciences, 50009 Kaunas, Lithuania
Antanas Gulbinas, Limas Kupcinskas, Zilvinas Dambrauskas, Institute for Digestive Research, Medical Academy, Lithuanian University of Health Sciences, 50009 Kaunas, Lithuania
Antanas Gulbinas, Juozas Pundzius, Zilvinas Dambrauskas, Department of Surgery, Medical Academy, Lithuanian University of Health Sciences, 50009 Kaunas, Lithuania
Johannes Cremers, Eugene Jansen, Centre for Health Protection National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
Author contributions: Jansen E, Gulbinas A, Dambrauskas Z and Pundzius J designed the research; Kuliaviene I, Dambrauskas Z and Cremers J performed the research; Kuliaviene I, Jansen E, Cremers J, Kupcinskas L and Pundzius J analysed and interpreted the data; Kuliaviene I drafted the article; Jansen E, Gulbinas A, Cremers J, Pundzius J, Kupcinskas L and Dambrauskas Z revised the article for important intellectual content, finally approved the version to be published.
Correspondence to: Irma Kuliaviene, MD, Department of Gastroenterology, Medical Academy, Lithuanian University of Health Sciences, Eiveniu 2, 50009 Kaunas, Lithuania. irma.kuliaviene@gmail.com
Telephone: +370-37-326430 Fax: +370-37-326508
Received: April 19, 2013
Revised: June 3, 2013
Accepted: June 19, 2013
Published online: September 14, 2013
Processing time: 147 Days and 16.2 Hours
Core Tip

Core tip: The manuscript by Kuliaviene et al elucidates the changes of fatty acids in erythrocyte membrane phospholipids during acute pancreatitis. Alcohol may influence the increased percentage of saturated and monounsaturated fatty acids of erythrocyte membrane. Fatty acids that are linked with inflammatory processes change differently during severe and mild nonalcoholic acute pancreatitis. The decrease of pro-inflammatory acids is seen in severe acute pancreatitis while anti-inflammatory players decrease during mild acute pancreatitis. The antioxidant enzymes of erythrocytes change in mild but not severe pancreatitis group. Thus the erythrocyte membranes can reflect the inflammatory and oxidative processes of acute pancreatitis.