Wang JS, Shi JS, Xu YZ, Duan XY, Zhang L, Wang J, Yang LM, Weng SF, Wu JG. FT-IR spectroscopic analysis of normal and cancerous tissues of esophagus. World J Gastroenterol 2003; 9(9): 1897-1899 [PMID: 12970871 DOI: 10.3748/wjg.v9.i9.1897]
Corresponding Author of This Article
Jing-Sen Shi, Laboratory of Hepatobiliary Surgery, First Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China. wjsdxy@263.net
Article-Type of This Article
Esophageal Cancer
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Wang JS, Shi JS, Xu YZ, Duan XY, Zhang L, Wang J, Yang LM, Weng SF, Wu JG. FT-IR spectroscopic analysis of normal and cancerous tissues of esophagus. World J Gastroenterol 2003; 9(9): 1897-1899 [PMID: 12970871 DOI: 10.3748/wjg.v9.i9.1897]
Jian-Sheng Wang, Jing-Sen Shi, Xiao-Yi Duan, Department of Oncological Surgery, First Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
Yi-Zhuang Xu, Li Zhang, Li-Ming Yang, Shi-Fu Weng, Jin-Guang Wu, Institute of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
Jing Wang, Department of Pathology, Oral Medical Hospital, Peking University, Beijing 100871, China
Author contributions: All authors contributed equally to the work.
Supported by the National Natural Science Foundation of China, No. 39730160
Correspondence to: Jing-Sen Shi, Laboratory of Hepatobiliary Surgery, First Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China. wjsdxy@263.net
Telephone: +86-29-5323527 Fax: +86-29-5263190
Received: May 12, 2003 Revised: May 23, 2003 Accepted: June 2, 2003 Published online: September 15, 2003
Abstract
AIM: To investigate the special Fourier transform infrared spectroscopy (FT-IR) spectra in normal and cancerous tissues of esophagus.
METHODS: Twenty-seven pairs of normal and cancerous tissues of esophagus were studied by using FT-IR and the special spectra characteristics were analyzed in different tissues.
RESULTS: Different spectra were found in normal and cancerous tissues. The peak at 1550/cm was weak and wide in cancerous tissues but strong and high in normal tissues.The ratio of I 1647/I 1550 was 2.0 in normal tissues and 2.36 in cancerous tissues (P < 0.05). The ratio of I 1550/I 1080 was 4.5 in normal tissues and 3.4 in cancerous tissues (P < 0.01). The peak at 1453/cm was higher than at 1402/cm in normal tissue and lower than at 1402/cm in cancerous tissues.
CONCLUSION: The results indicate that FTIR may be used in clinical diagnosis.
