Wang JJ, Xu WL, Li AQ. Aggressive angiomyxoma occurring in the stomach: A case report and review of literature. World J Gastroenterol 2026; 32(15): 115263 [DOI: 10.3748/wjg.v32.i15.115263]
Corresponding Author of This Article
Ai-Qing Li, PhD, Doctor, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qinchun Road, Hangzhou 310003, Zhejiang Province, China. 3310015@zju.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Apr 21, 2026 (publication date) through Apr 15, 2026
Times Cited of This Article
Times Cited (0)
Journal Information of This Article
Publication Name
World Journal of Gastroenterology
ISSN
1007-9327
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Wang JJ, Xu WL, Li AQ. Aggressive angiomyxoma occurring in the stomach: A case report and review of literature. World J Gastroenterol 2026; 32(15): 115263 [DOI: 10.3748/wjg.v32.i15.115263]
World J Gastroenterol. Apr 21, 2026; 32(15): 115263 Published online Apr 21, 2026. doi: 10.3748/wjg.v32.i15.115263
Aggressive angiomyxoma occurring in the stomach: A case report and review of literature
Jing-Jie Wang, Wen-Li Xu, Ai-Qing Li
Jing-Jie Wang, Ai-Qing Li, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Wen-Li Xu, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang University, Hangzhou 310058, Zhejiang Province, China
Author contributions: Wang JJ was the primary data collector and writer, and is the first author; Li AQ was the co-corresponding author; Wang JJ, Xu WL and Li AQ have read and approved the final version to be published.
Informed consent statement: Informed consent was obtained from the patient for the publication of their information and imaging.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Ai-Qing Li, PhD, Doctor, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qinchun Road, Hangzhou 310003, Zhejiang Province, China. 3310015@zju.edu.cn
Received: October 15, 2025 Revised: November 23, 2025 Accepted: February 5, 2026 Published online: April 21, 2026 Processing time: 184 Days and 12.8 Hours
Abstract
BACKGROUND
Aggressive angiomyxoma (AA) is a rare, slow-growing, locally invasive mesenchymal tumor classified as an undifferentiated neoplasm under the World Health Organization classification system. It predominantly occurs in the vagina, vulva, and other pelvic soft tissues, although its clinical manifestations can be highly variable.
CASE SUMMARY
We report a case of AA located in the lesser curvature of the gastric antrum in a middle-aged female who presented with a palpable abdominal mass of one week’s duration. The patient subsequently underwent en bloc tumor resection, with histological confirmation of the diagnosis of gastric AA. Currently, there are no signs of tumor recurrence, and the patient’s general condition is satisfactory.
CONCLUSION
To our knowledge, this represents the second reported case of gastric-origin AA worldwide. AA arising in the stomach remains difficult to differentiate radiologically, and further clinical data are needed for comprehensive analysis in the future.
Core Tip: Aggressive angiomyxoma is a rare, slow-growing, locally invasive mesenchymal tumor. We present a case of aggressive angiomyxoma located in the stomach in a female, with a comprehensive review of its imaging features of endoscopic ultrasound, computed tomography, and magnetic resonance imaging.
