Nannini G, Amedei A. Women health and microbiota: Different aspects of well-being. World J Gastroenterol 2024; 30(10): 1287-1290 [PMID: 38596491 DOI: 10.3748/wjg.v30.i10.1287]
Corresponding Author of This Article
Amedeo Amedei, MSc, Full Professor, Department of Experimental and Clinical Medicine, University of Florence, 3 Largo Brambilla, Florence 50134, Italy. amedeo.amedei@unifi.it
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Mar 14, 2024; 30(10): 1287-1290 Published online Mar 14, 2024. doi: 10.3748/wjg.v30.i10.1287
Women health and microbiota: Different aspects of well-being
Giulia Nannini, Amedeo Amedei
Giulia Nannini, Amedeo Amedei, Department of Experimental and Clinical Medicine, University of Florence, Florence 50134, Italy
Amedeo Amedei, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Florence 50134, Italy
Author contributions: Nannini G and Amedei A designed the overall concept and outline of the manuscript; Nannini G and Amedei A contributed to the writing, and editing the manuscript; Nannini G reviewed the literature; Amedei A supervised and revised the manuscript; both authors have read and approve the final manuscript.
Conflict-of-interest statement: The authors declare no conflict of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Amedeo Amedei, MSc, Full Professor, Department of Experimental and Clinical Medicine, University of Florence, 3 Largo Brambilla, Florence 50134, Italy. amedeo.amedei@unifi.it
Received: December 23, 2023 Peer-review started: December 23, 2023 First decision: January 9, 2024 Revised: January 22, 2024 Accepted: February 25, 2024 Article in press: February 25, 2024 Published online: March 14, 2024 Processing time: 82 Days and 5.3 Hours
Abstract
In this editorial, we comment on the article by Marano et al recently published in the World Journal of Gastroenterology 2023; 29 (45): 5945-5952. We focus on the role of gut microbiota (GM) in women’s health, highlighting the need to thoroughly comprehend the sex differences in microbiota. Together, the host and GM support the host’s health. The microbiota components consist of viruses, bacteria, fungi, and archaea. This complex is an essential part of the host and is involved in neurological development, metabolic control, immune system dynamics, and host dynamic homeostasis. It has been shown that differences in the GM of males and females can contribute to chronic diseases, such as gastrointestinal, metabolic, neurological, cardiovascular, and respiratory illnesses. These differences can also result in some sex-specific changes in immunity. Every day, research on GM reveals new and more expansive frontiers, offering a wealth of innovative opportunities for preventive and precision medicine.
Core Tip: The intestinal microbiota, comprising viruses, bacteria, fungi, and archaea, plays a crucial role in neurological development, metabolic control, immune system dynamics, and overall host homeostasis. Differences in gut microbiota between males and females are suggested to contribute to various chronic diseases, including gastrointestinal, metabolic, neurological, cardiovascular, and respiratory illnesses, as well as sex-specific changes in immunity. The editorial highlights the ongoing research in the field, revealing new opportunities for innovative approaches in preventive and precision medicine.
