Li ZQ, LingHu EQ, Hu M, Li WM, Huang QY, Zhao YW. Esophageal variceal pressure influence on the effect of ligation. World J Gastroenterol 2015; 21(13): 3888-3892 [PMID: 25852273 DOI: 10.3748/wjg.v21.i13.3888]
Corresponding Author of This Article
En-Qiang LingHu, MD, Professor, Chief Physician, Department of Hepatology and Gastroenterology, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. linghuenqiang@vip.sina.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Basic Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Zhi-Qun Li, En-Qiang LingHu, Qi-Yang Huang, Yong-Wei Zhao, Department of Hepatology and Gastroenterology, Chinese PLA General Hospital, Beijing 100853, China
Zhi-Qun Li, Min Hu, Department of Gastroenterology and Hepatology, Chinese PLA 261 Hospital, Beijing 100094, China
Wei-Min Li, Gynaecology and Obstetrics, Pinggu District Hospital, Beijing 101200, China
Author contributions: LingHu EQ designed this research; Li ZQ performed this research, participated in the design, and drafted the manuscript; Hu M and Li WM carried out this research; Huang QY and Zhao YW participated in its design and coordination; all authors read and approved the final manuscript.
Supported by Special Financial Grant from the China Postdoctoral Science Foundation, No. 2012T50868; and Beijing Municipal Committee and Municipal Government Priority Access to the District Project of Emergency Startup Funds, No. Z111107056811048.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: En-Qiang LingHu, MD, Professor, Chief Physician, Department of Hepatology and Gastroenterology, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. linghuenqiang@vip.sina.com
Telephone: +86-10-68182255 Fax: +86-10-68154653
Received: August 24, 2014 Peer-review started: August 24, 2014 First decision: September 27, 2014 Revised: October 13, 2014 Accepted: December 5, 2014 Article in press: December 8, 2014 Published online: April 7, 2015 Processing time: 226 Days and 6.1 Hours
Abstract
AIM: To explore the effect of in vitro porcine esophageal variceal pressure on complete ligation degree for polycyclic ligators.
METHODS: An in vitro model of experimental porcine venous vessels was used to test various venous pressures. Three treatment groups were designated according to the preset pressure range: P1 = 25-30 cmH2O; P2 = 35-40 cmH2O; P3 = 45-50 cmH2O. The effect of pressure on ligation was assessed and compared among the groups.
RESULTS: Complete ligation was achieved at a rate of 56.25% (18/32) in group P1, 37.5% (12/32) in group P2, and 33.33% (11/33) in group P3 (χ2 = 3.6126; P = 0.0573).
CONCLUSION: Higher variceal pressures impair the ligation completion rate. Therefore, measuring variceal pressure may help predict the effect of endoscopic ligation and guide treatment choice.
Core tip: This study aims to explore the factors influencing rebleeding after endoscopic variceal ligation, and provide the theoretic basis for prevention and reduction of rebleeding after the procedure.
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Li ZQ, LingHu EQ, Hu M, Li WM, Huang QY, Zhao YW. Esophageal variceal pressure influence on the effect of ligation. World J Gastroenterol 2015; 21(13): 3888-3892 [PMID: 25852273 DOI: 10.3748/wjg.v21.i13.3888]
