Shoichiro Kawai, Tsutomu Nishida, Yoshito Hayashi, Hisao Ezaki, Takuya Yamada, Shinichiro Shinzaki, Masanori Miyazaki, Takayuki Yakushijin, Kenji Watabe, Hideki Iijima, Masahiko Tsujii, Tetsuo Takehara, Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Kei Nakai, Kohji Nishida, Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Author contributions: Kawai S and Nishida T contributed equally to this work and wrote the paper; Hayashi Y, Ezaki H, Yamada T, Shinzaki S, Miyazaki M, Nakai K, Yakushijin T, Watabe K, Iijima H, Tsujii M, Nishida K and Takehara T revised the paper.
Correspondence to: Tetsuo Takehara, MD, PhD, Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. takehara@gh.med.osaka-u.ac.jp
Telephone: +81-6-68793621 Fax: +81-6-68793629
Received: August 31, 2012 Revised: September 13, 2012 Accepted: October 30, 2012 Published online: March 7, 2013 Processing time: 193 Days and 1.7 Hours
Abstract
Choroidal or cutaneous metastasis of gastric cancer is rare. Gastrointestinal cancer was found in only 4% in patients with uveal metastasis. Choroidal metastasis from gastric cancer was reported in two cases in earlier literature. The frequency of gastric cancer as a primary lesion was 6% in cutaneous metastasis of men, and cutaneous metastasis occurs in 0.8% of all gastric cancers. We report a patient with gastric adenocarcinoma who presented with visual disorder in his left eye and skin pain on his head as his initial symptoms. These symptoms were diagnosed to be caused by choroidal and cutaneous metastasis of gastric adenocarcinoma. Two cycles of chemotherapy consisted of oral S-1 and intravenous cisplatin (SPIRITS regimen); this was markedly effective to reduce the primary gastric lesion and almost all the metastatic lesions.
