Case Report
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Feb 7, 2008; 14(5): 812-814
Published online Feb 7, 2008. doi: 10.3748/wjg.14.812
Coincidence of hepatocelluar carcinoma and hepatic angiomyolipomas in tuberous sclerosis complex: A case report
Bin Yang, Wen-Hui Chen, Pei-Zhi Shi, Jing-Jing Xiang, Ru-Jun Xu, Ji-Hong Liu
Bin Yang, Wen-Hui Chen, Pei-Zhi Shi, Department of Radiology, Hang Zhou First People's Hospital, Hangzhou 310006, Zhejiang Province, China
Jing-Jing Xiang, Ru-Jun Xu, Department of Pathology, Hang Zhou First People's Hospital, Hangzhou 310006, Zhejiang Province, China
Ji-Hong Liu, Department of Oncology, Hang Zhou First People's Hospital, Hangzhou 310006, Zhejiang Province, China
Correspondence to: Dr. Bin Yang, Department of Radiology, Hangzhou First People's Hospital, Hangzhou 310006, Zhejiang Province, China. yb1974126@sina.com
Telephone: +86-571-87065701-10256
Fax: +86-571-87065701
Received: September 25, 2007
Revised: December 3, 2007
Published online: February 7, 2008
Abstract

Tuberous sclerosis complex (TSC) is a dominantly inherited disorder which characterized by the growth of hamartomatous in multiple organs. Unlike the common development of renal angiomyolipoma, hepatic angiomyolipoma rarely occur in patients with TSC. We report here a patient with hepatic angiomyolipomas and concurrent hepatocellular carcinoma in TSC. This represents the first reported case in English literature. In this patient, multiple hepatic angiomyolipomas were diagnosed with recognition of their fat components and typical clinical settings. Hepatocellular carcinoma in the left liver lobe was definitely diagnosed by US guided biopsy. In such clinical settings, fat containing lesions in liver can be reasonably treated as angiomyolipomas, but non fat containing lesions must be differentiated from hepatocellular carcinoma, imaging guided biopsy can be adopted to confirm the diagnosis.

Keywords: Angiomyolipoma; Liver; Tuberous sclerosis complex; X-ray computed tomography; Ultrasonography