Case Report
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jul 14, 2008; 14(26): 4253-4256
Published online Jul 14, 2008. doi: 10.3748/wjg.14.4253
Coexistence of esophageal blue nevus, hair follicles and basaloid squamous carcinoma: A case report
Dong-Guan Wang, Xin-Gong Li, Hong Gao, Xi-Yin Sun, Xiao-Qiu Zhou
Dong-Guan Wang, Xin-Gong Li, Hong Gao, Xi-Yin Sun, Xiao-Qiu Zhou, Department of Pathology, Dongying People’s Hospital, Dongying 257091, Shandong Province, China
Author contributions: Wang DG, Li XG and Gao H contributed equally to this work; Wang DG, Li XG and Sun XY designed the research; Wang DG, Sun XY and Zhou XQ performed the research; Wang DG, Li XG, Sun XY and Zhou XQ wrote the paper.
Correspondence to: Dong-Guan Wang, PhD, Department of Pathology, Dongying People’s Hospital, Dongying 257091, Shandong Province, China. wangdongguan@126.com
Telephone: +86-546-8328653
Fax: +86-546-8339221
Received: April 18, 2008
Revised: May 23, 2008
Accepted: May 30, 2008
Published online: July 14, 2008
Abstract

We present the case of a 57-year-old man who underwent esophagectomy for esophageal carcinoma found at barium meal and gastroscopic examination. He was diagnosed as esophageal basaloid squamous carcinoma (BSC) and gastric stromal tumor, which were associated with focal proliferation of melanocytes/pigmentophages and hair follicles in esophageal mucosa. Melanocytic hyperplasia (melanocytosis) has previously been recognized as an occasional reactive lesion, which can accompany esophageal inflammation and invasive squamous carcinoma. The present case is unusual because of its hyperplasia of not only melanocytes but also hair follicles. To our knowledge, this is the first report of esophageal blue nevus and hair follicle coexisting with BSC.

Keywords: Esophagus; Basaloid squamous carcinoma; Blue nevus; Hair follicle; Gastric stromal tumor