Nomura K, Tomikashi K, Matsumoto Y, Yoshida N, Okuda T, Sakakura C, Mitsufuji S, Horiike S, Yamagishi H, Okanoue T, Taniwaki M. Small bowel non-Hodgkin's lymphoma remaining in complete remission by surgical resection and adjuvant rituximab therapy. World J Gastroenterol 2005; 11(28): 4443-4444 [PMID: 16038051 DOI: 10.3748/wjg.v11.i28.4443]
Corresponding Author of This Article
Kenichi Nomura, MD, PhD, Molecular Hematology and Oncology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-0841, Japan. nomuken@sun.kpu-m.ac.jp
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Kenichi Nomura, Yosuke Matsumoto, Shigeo Horiike, Molecular Hematology and Oncology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Koichi Tomikashi, Naohisa Yoshida, Takashi Okuda, Shoji Mitsufuji, Takeshi Okanoue, Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Chohei Sakakura, Hisakazu Yamagishi, Department of Surgery, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Masafumi Taniwaki, Clinical Molecular Genetics and Laboratory Medicine, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Author contributions: All authors contributed equally to the work.
Correspondence to: Kenichi Nomura, MD, PhD, Molecular Hematology and Oncology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-0841, Japan. nomuken@sun.kpu-m.ac.jp
Telephone: +81-75-251-5521 Fax: +81-75-251-0710
Received: June 15, 2004 Revised: July 13, 2004 Accepted: July 17, 2004 Published online: July 28, 2005
Abstract
A 44-year-old man was referred to our hospital with intermittent abdominal pain. Because distention of fluid- and gas-filled loops of small intestine was proved by X-ray, the patient was diagnosed as having small bowel obstruction. A laparotomy revealed a segmental stenosis in the jejunum, which showed diffuse thickening of the intestinal wall. Some mesenteric lymph nodes were swollen. Pathological examination was defined. We diagnosed diffuse large B-cell lymphoma based on the pathological findings of diffuse transmural infiltration of large lymphoid cells and flow-cytometric analyses. Rituximab was administered as adjuvant therapy at weekly doses of 375 mg/m2. Four cycles were performed every 6 mo and he remained CR. Rituximab may be effective as adjuvant therapy.
