Case Report
Copyright ©The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 15, 2004; 10(16): 2452-2454
Published online Aug 15, 2004. doi: 10.3748/wjg.v10.i16.2452
Granular cell tumor of colon: Report of a case and review of literature
Dae-Kyung Sohn, Hyo-Seong Choi, Yeon-Soo Chang, Jin-Myeong Huh, Dae-Hyun Kim, Dae-Yong Kim, Young-Hoon Kim, Hee-Jin Chang, Kyung-Hae Jung, Seung-Yong Jeong
Dae-Kyung Sohn, Hyo-Seong Choi, Yeon-Soo Chang, Jin-Myeong Huh, Dae-Hyun Kim, Dae-Yong Kim, Young-Hoon Kim, Hee-Jin Chang, Kyung-Hae Jung, Seung-Yong Jeong, Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi 411-769, Korea
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Seung-Yong Jeong, Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, 809 Madu-dong, Ilsan-gu, Goyang, Gyeonggi 411-769, Korea. syjeong@ncc.re.kr
Telephone: +82-31-920-1632 Fax: +82-31-920-0002
Received: March 15, 2004
Revised: March 26, 2004
Accepted: April 9, 2004
Published online: August 15, 2004
Abstract

Granular cell tumor (GCT) is uncommon in the colon and rectum. Here we report a case of GCT in the transverse colon. A 48-year-old male patient underwent a screening colonoscopy. A yellowish sessile lesion, about 4 mm in diameter, was found in the transverse colon. An endoscopic snare resection was performed without complication. Histological examination revealed the tumor consisted of plump neoplastic cells with abundant granular eosinophilic cytoplasm containing acidophilic periodic acid Schiff-positive, diastase-resistant granules. Immunohistochemical analysis showed the tumor cells expressed S-100 protein and neuron-specific enolase. Thus, the resected tumor was diagnosed as a GCT. Since GCTs are usually benign, endoscopic resection constitutes an easy and safe treatment. Colonoscopists should consider the possibility of GCT in the differential diagnosis of submucosal tumors of the colon.

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