Citation of this article
Corresponding Author of This Article
Research Domain of This Article
Article-Type of This Article
Open-Access Policy of This Article
Times Cited Counts in Google of This Article
Number of Hits and Downloads for This Article
- Total Article Views (10000)
All Articles published online
|
Publishing Process of This Article
|
Nov 14, 2012 (publication date) through Feb 18, 2025
Times Cited of This Article
Journal Information of This Article
Publication Name
World Journal of Gastroenterology
ISSN
1007-9327
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| For: | Sookoian S, Pirola CJ. PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease. World J Gastroenterol 2012; 18(42): 6018-6026 [PMID: 23155331 DOI: 10.3748/wjg.v18.i42.6018] |
|---|---|
| URL: | https://www.wjgnet.com/1007-9327/full/v18/i42/6018.htm |
| Number | Citing Articles |
| 1 |
Silvia Sookoian, Carlos Jose Pirola. Alcoholic and Non-Alcoholic Fatty Liver Disease. 2016; : 147 doi: 10.1007/978-3-319-20538-0_7
|
| 2 |
Rosalinda Posadas-Sánchez, Ángel René López-Uribe, Carlos Posadas-Romero, Nonanzit Pérez-Hernández, José Manuel Rodríguez-Pérez, Wendy Angélica Ocampo-Arcos, José Manuel Fragoso, Guillermo Cardoso-Saldaña, Gilberto Vargas-Alarcón. Association of the I148M/PNPLA3 (rs738409) polymorphism with premature coronary artery disease, fatty liver, and insulin resistance in type 2 diabetic patients and healthy controls. The GEA study. Immunobiology 2017; 222(10): 960 doi: 10.1016/j.imbio.2016.08.008
|
| 3 |
Tong Mu, Linrui Peng, Xinglei Xie, He He, Qing Shao, Xiran Wang, Yuwei Zhang, Guo Chen. Single Nucleotide Polymorphism of Genes Associated with Metabolic Fatty Liver Disease. Journal of Oncology 2022; 2022: 1 doi: 10.1155/2022/9282557
|
| 4 |
Nikolaos Perakakis, Konstantinos Stefanakis, Christos S. Mantzoros. The role of omics in the pathophysiology, diagnosis and treatment of non-alcoholic fatty liver disease. Metabolism 2020; 111: 154320 doi: 10.1016/j.metabol.2020.154320
|
| 5 |
Maoyin Li, Xuemin Wang. Phospholipases in Plant Signaling. Signaling and Communication in Plants 2014; 20: 93 doi: 10.1007/978-3-642-42011-5_5
|
| 6 |
Kendra A. Young, Nicholette D. Palmer, Tasha E. Fingerlin, Carl D. Langefeld, Jill M. Norris, Nan Wang, Anny H. Xiang, Xiuqing Guo, Adrienne H. Williams, Yii‐Der I. Chen, Kent D. Taylor, Jerome I. Rotter, Leslie J. Raffel, Mark O. Goodarzi, Richard M. Watanabe, Lynne E. Wagenknecht. Genome‐Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium. Obesity 2019; 27(8): 1331 doi: 10.1002/oby.22527
|
| 7 |
Takashi Ide. γ-Linolenic Acid-Rich Oil- and Fish Oil-Induced Alterations of Hepatic Lipogenesis, Fatty Acid Oxidation, and Adipose Tissue mRNA Expression in Obese KK-<i>A</i> <sup> <i>y</i> </sup> Mice. Journal of Oleo Science 2023; 72(3): 313 doi: 10.5650/jos.ess22341
|
| 8 |
Renfan Xu, Anyu Tao, Shasha Zhang, Youbin Deng, Guangzhi Chen. Association Between Patatin-Like Phospholipase Domain Containing 3 Gene (PNPLA3) Polymorphisms and Nonalcoholic Fatty Liver Disease: A HuGE Review and Meta-Analysis. Scientific Reports 2015; 5(1) doi: 10.1038/srep09284
|
| 9 |
Paola Dongiovanni, Marica Meroni, Miriam Longo, Silvia Fargion, Anna Ludovica Fracanzani. miRNA Signature in NAFLD: A Turning Point for a Non-Invasive Diagnosis. International Journal of Molecular Sciences 2018; 19(12): 3966 doi: 10.3390/ijms19123966
|
| 10 |
Kyu-Ho Han, Naoto Hashimoto, Michihiro Fukushima. Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes. World Journal of Gastroenterology 2016; 22(1): 37-49 doi: 10.3748/wjg.v22.i1.37
|
| 11 |
Carolina M. Machado, Nathalie C. Leite, Paulo H. França, Claudia R. Cardoso, Gil F. Salles, Cristiane A. Villela-Nogueira. PNPLA3 gene polymorphism in Brazilian patients with type 2 diabetes: A prognostic marker beyond liver disease?. Nutrition, Metabolism and Cardiovascular Diseases 2019; 29(9): 965 doi: 10.1016/j.numecd.2019.06.002
|
| 12 |
Anjeza Pashaj, Xiaohua Yi, Mengna Xia, Stephanie Canny, Jean-Jack M. Riethoven, Régis Moreau. Characterization of genome-wide transcriptional changes in liver and adipose tissues of ZDF (fa/fa) rats fed R-α-lipoic acid by next-generation sequencing. Physiological Genomics 2013; 45(23): 1136 doi: 10.1152/physiolgenomics.00138.2013
|
| 13 |
Trina M. Norden-Krichmar, Daniel Rotroff, Tae-Hwi Schwantes-An, Ramon Bataller, David Goldman, Laura E. Nagy, Suthat Liangpunsakul. Genomic approaches to explore susceptibility and pathogenesis of alcohol use disorder and alcohol-associated liver disease. Hepatology 2023; doi: 10.1097/HEP.0000000000000617
|
| 14 |
Silvia Sookoian, Carlos J Pirola. Personalizing Care for Nonalcoholic Fatty Liver Disease Patients: What are the Research Priorities?. Personalized Medicine 2014; 11(8): 735 doi: 10.2217/pme.14.44
|
| 15 |
Guobo Li, Xingyan Xu, Le Yang, Yingying Cai, Yi Sun, Jianhui Guo, Yawen Lin, Yuduan Hu, Mingjun Chen, Huangyuan Li, Siying Wu. Exploring the association between circRNA expression and pediatric obesity based on a case–control study and related bioinformatics analysis. BMC Pediatrics 2023; 23(1) doi: 10.1186/s12887-023-04261-1
|
| 16 |
Carlos J. Pirola, Silvia Sookoian. PNPLA3 and COVID‐19 outcomes: Thinking outside the box might explain the biology behind pleiotropic effects of rs738409 on the immune system. Liver International 2021; 41(11): 2801 doi: 10.1111/liv.15043
|
| 17 |
Maria V. Bourganou, Maria Eleni Chondrogianni, Ioannis Kyrou, Christina-Maria Flessa, Antonios Chatzigeorgiou, Evangelos Oikonomou, Vaia Lambadiari, Harpal S. Randeva, Eva Kassi. Unraveling Metabolic Dysfunction-Associated Steatotic Liver Disease Through the Use of Omics Technologies. International Journal of Molecular Sciences 2025; 26(4): 1589 doi: 10.3390/ijms26041589
|
| 18 |
Xiao Xu, Xiaojie Deng, Yunzhi Chen, Wen Xu, Fen Xu, Hua Liang. SIRT1 mediates nutritional regulation of SREBP-1c-driven hepatic PNPLA3 transcription via modulation of H3k9 acetylation. Genes and Environment 2022; 44(1) doi: 10.1186/s41021-022-00246-1
|
| 19 |
Silvia Sookoian, Carlos J Pirola. Liver enzymes, metabolomics and genome-wide association studies: From systems biology to the personalized medicine. World Journal of Gastroenterology 2015; 21(3): 711-725 doi: 10.3748/wjg.v21.i3.711
|
| 20 |
Jiapeng Chen, Alexandra Montagner, Nguan Soon Tan, Walter Wahli. Insights into the Role of PPARβ/δ in NAFLD. International Journal of Molecular Sciences 2018; 19(7): 1893 doi: 10.3390/ijms19071893
|
| 21 |
Praveen Sethupathy. Needles in the genetic haystack of lipid disorders: single nucleotide polymorphisms in the microRNA regulome. Journal of Lipid Research 2013; 54(5): 1168 doi: 10.1194/jlr.R035766
|
| 22 |
Carlos Jose Pirola, Silvia Sookoian. Epigenetics factors in nonalcoholic fatty liver disease. Expert Review of Gastroenterology & Hepatology 2022; 16(6): 521 doi: 10.1080/17474124.2020.1765772
|
| 23 |
|
| 24 |
Carlos J. Pirola, Silvia Sookoian. Repurposing drugs to target nonalcoholic steatohepatitis: Auranofin, a gold-organic molecule complex for the treatment of a specifc complex trait. Clinical and Molecular Hepatology 2022; 28(4): 806 doi: 10.3350/cmh.2022.0208
|
| 25 |
Suthat Liangpunsakul, Puneet Puri, Vijay H. Shah, Patrick Kamath, Arun Sanyal, Thomas Urban, Xiaowei Ren, Barry Katz, Svetlana Radaeva, Naga Chalasani, David W. Crabb, David Crabb, Naga Chalasani, Suthat Liangpunsakul, Barry Katz, Spencer Lourens, Andy Borst, Ryan Cook, Andy Qigui Yu, David Nelson, Romil Saxena, Sherrie Cummings, Megan Comerford, Lakye Edwards, Vijay Shah, Gregory Gores, Patrick Kamath, Vikas Verma, Sarah Wilder, Amy Olofson, Amanda Schimek, Arun Sanyal, Puneet Puri, Susan Walker, Svetlana Raedeva. Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis. Clinical Gastroenterology and Hepatology 2016; 14(12): 1831 doi: 10.1016/j.cgh.2016.05.041
|
| 26 |
Sepideh Mikaeeli, David E. Cohen. Loss or gain of function: The functional complexity of the PNPLA3 I148M Variant. Journal of Hepatology 2025; doi: 10.1016/j.jhep.2025.01.019
|
| 27 |
Oana Irina Gavril, Lidia Iuliana Arhire, Radu Sebastian Gavril, Madalina Ioana Zota, Andreea Gherasim, Otilia Nita, Andrei Drugescu, Andrei Catalin Oprescu, Irina Mihaela Esanu, Florin Mitu, Mariana Graur, Laura Mihalache. Correlations between PNPLA3 Gene Polymorphisms and NAFLD in Type 2 Diabetic Patients. Medicina 2021; 57(11): 1249 doi: 10.3390/medicina57111249
|
| 28 |
Christopher J. Schmoyer, Mohammad S. Siddiqui. Non-alcoholic Fatty Liver Disease in Non-obese Patients. Current Hepatology Reports 2017; 16(4): 382 doi: 10.1007/s11901-017-0377-3
|
| 29 |
Silvia Sookoian, Carlos J. Pirola. Genetic and Epigenetic Associations with NAFLD: Focus on Clinical Decision Making and Novel Concepts in Disease Pathogenesis. Current Hepatology Reports 2014; 13(2): 97 doi: 10.1007/s11901-014-0222-x
|
| 30 |
Giovanni Tarantino, Carmine Finelli. Handbook of Lipids in Human Function. 2016; : 85 doi: 10.1016/B978-1-63067-036-8.00004-4
|
| 31 |
Samar Samir Youssef, Rana Ahmed Youness, Eman Abd El-Razek Abbas, Noha Mohamed Osman, Asmaa ELFiky, Mohamed El-Kassas.
miR-516a-3P, a Potential Circulating Biomarker in Hepatocellular Carcinoma, Correlated with
rs738409
Polymorphism in
PNPLA3
. Personalized Medicine 2022; 19(6): 483 doi: 10.2217/pme-2022-0005
|
| 32 |
Suki Ha, Vincent Wai-Sun Wong, Xiang Zhang, Jun Yu. Interplay between gut microbiome, host genetic and epigenetic modifications in MASLD and MASLD-related hepatocellular carcinoma. Gut 2025; 74(1): 141 doi: 10.1136/gutjnl-2024-332398
|
| 33 |
Dixa Sharma, Palash Mandal. NAFLD: genetics and its clinical implications. Clinics and Research in Hepatology and Gastroenterology 2022; 46(9): 102003 doi: 10.1016/j.clinre.2022.102003
|
| 34 |
Hugo da Costa Santos, Tanja Hess, Jason Bruemmer, Rebecca Splan. Possible Role of MicroRNA in Equine Insulin Resistance: A Pilot Study. Journal of Equine Veterinary Science 2018; 63: 74 doi: 10.1016/j.jevs.2017.10.024
|
| 35 |
Hilmar K Lückhoff, Frederik C Kruger, Maritha J Kotze. Composite prognostic models across the non-alcoholic fatty liver disease spectrum: Clinical application in developing countries. World Journal of Hepatology 2015; 7(9): 1192-1208 doi: 10.4254/wjh.v7.i9.1192
|
| 36 |
Chi-Ming Tai, Chih-Kun Huang, Hung-Pin Tu, Jau-Chung Hwang, Ming-Lun Yeh, Chung-Feng Huang, Jee-Fu Huang, Chia-Yen Dai, Wan-Long Chuang, Ming-Lung Yu. Interactions of a PPARGC1A Variant and a PNPLA3 Variant Affect Nonalcoholic Steatohepatitis in Severely Obese Taiwanese Patients. Medicine 2016; 95(12): e3120 doi: 10.1097/MD.0000000000003120
|
| 37 |
Michael Doulberis, Georgios Kotronis, Dimitra Gialamprinou, Jannis Kountouras, Panagiotis Katsinelos. Non-alcoholic fatty liver disease: An update with special focus on the role of gut microbiota. Metabolism 2017; 71: 182 doi: 10.1016/j.metabol.2017.03.013
|
| 38 |
Giovanni Tarantino, Carmine Finelli. Handbook of Lipids in Human Function. 2016; : 731 doi: 10.1016/B978-1-63067-036-8.00028-7
|
| 39 |
Suthat Liangpunsakul, Paul Haber, Geoffrey W. McCaughan. Alcoholic Liver Disease in Asia, Europe, and North America. Gastroenterology 2016; 150(8): 1786 doi: 10.1053/j.gastro.2016.02.043
|
| 40 |
Anna Di Sessa, Simona Riccio, Emilia Pirozzi, Martina Verde, Antonio Paride Passaro, Giuseppina Rosaria Umano, Stefano Guarino, Emanuele Miraglia del Giudice, Pierluigi Marzuillo. Advances in paediatric nonalcoholic fatty liver disease: Role of lipidomics. World Journal of Gastroenterology 2021; 27(25): 3815-3824 doi: 10.3748/wjg.v27.i25.3815
|
| 41 |
Suthat Liangpunsakul, David W. Crabb. Zakim and Boyer's Hepatology. 2018; : 345 doi: 10.1016/B978-0-323-37591-7.00023-9
|
| 42 |
Piero Pingitore, Stefano Romeo. The role of PNPLA3 in health and disease. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2019; 1864(6): 900 doi: 10.1016/j.bbalip.2018.06.018
|
| 43 |
|
| 44 |
Xiaocheng Charlie Dong. PNPLA3—A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease. Frontiers in Medicine 2019; 6 doi: 10.3389/fmed.2019.00304
|
| 45 |
Carlos J Pirola, Silvia Sookoian. Advances in our understanding of the molecular heterogeneity of fatty liver disease: toward informed treatment decision making. Expert Review of Gastroenterology & Hepatology 2023; 17(4): 317 doi: 10.1080/17474124.2023.2191190
|
| 46 |
Bedair Dewidar, Lucia Mastrototaro, Cornelia Englisch, Claudia Ress, Cesare Granata, Elisabeth Rohbeck, Dominik Pesta, Geronimo Heilmann, Martin Wolkersdorfer, Irene Esposito, Michelle Reina Do Fundo, Fariba Zivehe, Aslihan Yavas, Michael Roden. Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases. eBioMedicine 2023; 94: 104714 doi: 10.1016/j.ebiom.2023.104714
|
| 47 |
Eric Trépo, Stefano Romeo, Jessica Zucman-Rossi, Pierre Nahon. PNPLA3 gene in liver diseases. Journal of Hepatology 2016; 65(2): 399 doi: 10.1016/j.jhep.2016.03.011
|
| 48 |
Silvia Sookoian, Carlos J. Pirola. Genetic predisposition in nonalcoholic fatty liver disease. Clinical and Molecular Hepatology 2017; 23(1): 1 doi: 10.3350/cmh.2016.0109
|
| 49 |
Gemma Aragonès, Teresa Auguet, Sandra Armengol, Alba Berlanga, Esther Guiu-Jurado, Carmen Aguilar, Salomé Martínez, Fátima Sabench, José Porras, Maikel Ruiz, Mercé Hernández, Joan Sirvent, Daniel Del Castillo, Cristóbal Richart. PNPLA3 Expression Is Related to Liver Steatosis in Morbidly Obese Women with Non-Alcoholic Fatty Liver Disease. International Journal of Molecular Sciences 2016; 17(5): 630 doi: 10.3390/ijms17050630
|
| 50 |
Carlos Jose Pirola, Adrian Salatino, Silvia Sookoian. Pleiotropy within gene variants associated with nonalcoholic fatty liver disease and traits of the hematopoietic system. World Journal of Gastroenterology 2021; 27(4): 305-320 doi: 10.3748/wjg.v27.i4.305
|