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World J Gastroenterol. Jan 28, 2021; 27(4): 305-320
Published online Jan 28, 2021. doi: 10.3748/wjg.v27.i4.305
Pleiotropy within gene variants associated with nonalcoholic fatty liver disease and traits of the hematopoietic system
Carlos Jose Pirola, Adrian Salatino, Silvia Sookoian
Carlos Jose Pirola, Adrian Salatino, Department of Molecular Genetics and Biology of Complex Diseases, National Scientific and Technical Research Council (CONICET), University of Buenos Aires, Institute of Medical Research (IDIM), Ciudad Autónoma de Buenos Aires C1427ARO, Argentina
Carlos Jose Pirola, Adrian Salatino, Silvia Sookoian, Institute of Medical Research A Lanari, University of Buenos Aires, School of Medicine, Ciudad Autónoma de Buenos Aires, Ciudad Autónoma de Buenos Aires C1427ARO, Argentina
Silvia Sookoian, Department of Clinical and Molecular Hepatology, National Scientific and Technical Research Council (CONICET), University of Buenos Aires, Institute of Medical Research (IDIM), Ciudad Autónoma de Buenos Aires C1427ARO, Argentina
Author contributions: Pirola CJ contributed to study concept and design, data acquisition, data analysis and interpretation, statistical analysis, manuscript drafting, general study supervision and securing funding; Salatino A contributed to data acquisition and bioinformatic support; Sookoian S contributed to study concept and design, data acquisition, data analysis and interpretation, general study supervision, manuscript drafting, securing funding; Pirola CJ and Sookoian S should be considered joint senior authors.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Silvia Sookoian, FAASLD, MD, PhD, Senior Scientist, Department of Clinical and Molecular Hepatology, National Scientific and Technical Research Council (CONICET), University of Buenos Aires, Institute of Medical Research (IDIM), Combatientes de Malvinas 3150, Ciudad Autónoma de Buenos Aires 1427, Argentina. ssookoian@intramed.net
Received: November 9, 2020
Peer-review started: November 9, 2020
First decision: December 8, 2020
Revised: December 19, 2020
Accepted: December 27, 2020
Article in press: December 27, 2020
Published online: January 28, 2021
Processing time: 76 Days and 9.3 Hours
Core Tip

Core Tip: Pleiotropy within variants associated with hematologic traits and nonalcoholic fatty liver disease.