In 2017, the World Journal of Gastroenterology (WJG) has published the 48^th issue which containing 23 articles including 1 editorial, 3 reviews, 16 original articles and 3 case reports contributed by scientists worldwide. Among these comprehensive articles are (1) “Mechanisms of autophagy activation in endothelial cell and their targeting during normothermic machine liver perfusion”, a review by Dr. Ricky H Bhogal, et al from  the Centre for Liver Research, Institute for Biomedical Research, University of Birmingham, United Kingdom; (2) “Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights”, a basic study by Predrag Sikiric, MD, PhD, Professor, et al from Department of Pharmacology, School of Medicine, University of Zagreb, Croatia; and (3) “Prevalence and outcomes of pancreatic cystic neoplasms in liver transplant recipients”, a retrospective cohort study by Arthur J Kaffes, FRACP, MBBS, Associate Professor, et al from Sydney Medical School, University of Sydney, AW Morrow Gastroenterology and Liver Centre, Level 9, Royal Prince Alfred Hospital, Australia, etc. We invite you to peruse all 23 articles in this issue, as they present the latest research progress/findings and provide insightful comments in gastroenterology and hepatology that will guide basic research and clinical practice in these fields.

Figure 1 The cover of the issue. Editorial board member of World Journal of Gastroenterology, Paola Iovino, MD, Associate Professor, Lecturer, Department of Medicine and Surgery, AOU San Giovanni di Dio e Ruggi di Aragona, Salerno 84131, Italy

We encourage gastroenterologists and hepatologists worldwide to submit manuscripts to the WJG describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

We invited the readers to download and read the E-Journal of this issue.