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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Dec 28, 2020; 8(6): 462-471
Published online Dec 28, 2020. doi: 10.13105/wjma.v8.i6.462
Published online Dec 28, 2020. doi: 10.13105/wjma.v8.i6.462
Split-dose vs same-day bowel preparation for afternoon colonoscopies: A meta-analysis of randomized controlled trials
Nasim Parsa, Eric A Grisham, Courtney J Cockerell, Michelle L Matteson-Kome, Ramakrishna V Bysani, Sami Samiullah, Veysel Tahan, Yezaz A Ghouri, Matthew L Bechtold, Division of Gastroenterology and Hepatology, Department of Medicine, University of Missouri - Columbia, Columbia, MO 65212, United States
Douglas L Nguyen, Division of Gastroenterology, Heart of the Rockies Regional Medical Center, Colorado Springs, CO 80907, United States
Srinivas R Puli, Division of Gastroenterology, University of Illinois - Peoria, Peoria, IL 61604, United States
Author contributions: Parsa N, Cockerell CJ, and Bechtold ML designed the meta-analysis; Parsa N, Grisham EA, Cockerell CJ, and Bysani RV acquired the data; Matteson-Kome ML, Samiullah S, Nguyen DL, and Bechtold ML analyzed and interpreted the data; Parsa N, Grisham EA, Cockerell CJ, and Bysani RV drafted the manuscript; Samiullah S, Nguyen DL, Tahan V, Ghouri YA, Puli SR, and Bechtold ML critically revised the manuscript; and Matteson-Kome ML, Nguyen DL, Puli SR, and Bechtold ML provided statistical expertise.
Conflict-of-interest statement: The authors have no conflicts of interest for this manuscript.
PRISMA 2009 Checklist statement: The authors adhered to the PRISMA guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Matthew L Bechtold, AGAF, FACG, FACP, FASGE, MD, Attending Doctor, Professor, Division of Gastroenterology and Hepatology, Department of Medicine, University of Missouri - Columbia, 5 Hospital Drive, Columbia, MO 65212, United States. bechtoldm@health.missouri.edu
Received: July 15, 2020
Peer-review started: July 15, 2020
First decision: November 2, 2020
Revised: November 11, 2020
Accepted: November 21, 2020
Article in press: November 21, 2020
Published online: December 28, 2020
Processing time: 166 Days and 4.5 Hours
Peer-review started: July 15, 2020
First decision: November 2, 2020
Revised: November 11, 2020
Accepted: November 21, 2020
Article in press: November 21, 2020
Published online: December 28, 2020
Processing time: 166 Days and 4.5 Hours
Core Tip
Core Tip: Afternoon colonoscopies have considerably more inadequate bowel preparations than morning colonoscopies. Different bowel preparation regimens have been tried to help improve preparation quality in afternoon colonoscopies, including split-dose and same-day bowel preparations. Studies have shown conflicting results on which preparation regimen is optimal. Therefore, we conducted a meta-analysis on this subject and found that split-dose bowel preparation shows no difference in satisfactory bowel preparations vs same-day bowel preparation for afternoon colonoscopies. Therefore, either preparation may be utilized.