Published online Jun 28, 2021. doi: 10.13105/wjma.v9.i3.317
Peer-review started: April 23, 2021
First decision: June 7, 2021
Revised: June 13, 2021
Accepted: June 16, 2021
Article in press: June 16, 2021
Published online: June 28, 2021
Processing time: 79 Days and 15.1 Hours
Listeria monocytogenes (L. monocytogenes) is one of the most important zoonotic bacteria that is transmitted to humans through infected animal products and is the cause of human listeriosis. Pregnant women and immunocompromised patients are more susceptible to the bacterium than healthy people. Recent studies have reported extensive evidence on the role of L. monocytogenes infection and the risk of spontaneous abortion.
To evaluate the possible connection with L. monocytogenes in the risk of spontaneous abortion in pregnancy.
We conducted a systematic literature review using several databases to search the relevant case-control studies on the association between L. monocytogenes infection and spontaneous abortion. Finally, the impact of infection with L. monocytogenes and risk of spontaneous abortion was assessed via odds ratio at corresponding 95% confidence intervals.
In the present study, we evaluated the data of 4059 pregnant women who had a spontaneous abortion, and interestingly their colonization rate of L. monocytogenes was about 20.5%.
Therefore, based on statistical analysis, we found that there is a significant relationship between the infection with L. monocytogenes and spontaneous abortion.
Core Tip: Listeria monocytogenes is one of the most common bacterial infections among developing countries. Acquisition of this bacterium during pregnancy is dangerous for the health of neonates. Our results suggested that Listeria monocytogenes can significantly increase the risk of spontaneous abortion during pregnancy.