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World J Meta-Anal. Mar 31, 2019; 7(3): 96-100
Published online Mar 31, 2019. doi: 10.13105/wjma.v7.i3.96
Early immune response in post endoscopic retrograde cholangiopancreatography pancreatitis as a model for acute pancreatitis
Ivana Plavsic, Ivana Zitinic, Vera Tulic, Goran Poropat, Marinko Marusic, Goran Hauser
Ivana Plavsic, Vera Tulic, Department of Anesthesiology and Critical care medicine, Clinical Hospital Centre, Medical Faculty, University of Rijeka, Rijeka 51000, Croatia
Ivana Zitinic, Department of Emergency Medicine, Clinical Hospital Centre, Rijeka 51000, Croatia
Goran Poropat, Department of Internal Medicine, Division of Gastroenterology, Clinical Hospital Centre, Medical Faculty, Medical Faculty Rijeka, University of Rijeka, Rijeka 51000, Croatia
Marinko Marusic, Department of Internal Medicine, Division of Gastroenterology, Clinical Hospital Sv. Duh, Zagreb, Faculty of Health Studies, University of Rijeka, Rijeka 51000, Croatia
Marinko Marusic, Medical Faculty Osijek, University of J.J. Stossmayer, Osijek 31000, Croatia
Goran Hauser, Department of Internal Medicine, Division of Gastroenterology, Clinical Hospital Centre, Medical Faculty, Faculty of Health Studies, University of Rijeka, Rijeka 51000, Croatia
Author contributions: Plavsic I and Hauser G designed and conduct research and are the guarantors of this work; Plavsic I, Hauser G, Zitinic I, Tulic V, Poropat G contributed to the discussion, and reviewed and edited the manuscript; Plavsic I, Marusic M and Hauser G analyzed collected data; Plavsic I, Hauser G and Zitinic I wrote the paper.
Supported by University of Rijeka grant, No. 18.04.2.1.01.
Conflict-of-interest statement: The author has no conflict of interest to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Goran Hauser, MD, PhD, Research Assistant Professor, Department of Internal Medicine, Division of Gastroenterology, Clinical Hospital Centre, Medical Faculty, Faculty of Health Studies, University of Rijeka, Kresimirova 42, Rijeka 51000, Croatia. goran.hauser@medri.uniri.hr
Telephone: +385-51-568122 Fax: +385-51-658386
Received: February 10, 2019
Peer-review started: February 12, 2019
First decision: March 20, 2019
Revised: March 27, 2019
Accepted: March 27, 2019
Article in press: March 28, 2019
Published online: March 31, 2019
Processing time: 50 Days and 23.3 Hours
Abstract

This opinion review summarizes comparison of clinical presentation and immunology of post-endoscopic pancreatitis and acute pancreatitis (AP) of other etiology. The rationale for this topic was found in studies that mention differences in clinical presentation between these entities, stating that severe form of AP after endoscopic retrograde cholangiopancreatography was more severe than AP of other etiology. Found difference in clinical presentation may have a background in different immunology that needs to be further investigated.

Keywords: Innate immunity; Pancreatitis immunology; Post endoscopic retrograde cholangiopancreatography pancreatitis

Core tip: Innate immunity plays an immense role in the development of acute pancreatitis (AP) and may determine the course of the disease. Information about the role of innate immunity in patients with post-endoscopic pancreatitis (PEP) is still deficient. PEP may serve as an ideal model for further research of innate immunity function in AP development.