Value of GRACE and SYNTAX scores for predicting the prognosis of patients with non-ST elevation acute coronary syndrome

Table 1 Baseline characteristics of patients with non-ST-elevation acute coronary syndrome, n = 386

Items	n (%)
Age in yr, mean ± SD	61.25 ± 4.09
Gender
Male	243 (63.0)
Female	143 (37.0)
Unstable angina	327 (84.7)
Hypertension	262 (69.4)
Diabetes	95 (24.6)
Hyperlipidemia	62 (16.1)
Major adverse cardiovascular events	108 (28.0)
Recurrent angina	115 (29.8)
NYHA class I or above	17 (4.4)
Nonfatal recurrent myocardial infarction	8 (2.1)
Target vessel revascularization	22 (5.7)
Death	4 (1.0)
Number of stents	247 (64.0)
CABG	35 (9.1)

CABG: Coronary artery bypass grafting; NSTEACS: Non-ST elevation acute coronary syndrome; NYHA: New York Heart Association.

Table 2 Incidence of major adverse cardiovascular events in patients with different GRACE and SYNTAX scores, n = 386

Groups	n	MACE, n	Incidence of MACE, %	Hc value	P value
GRACE scores (points)				7.398	0.031
Low risk group (0-88)	95	13	13.7
Intermediate risk group (89-117)	151	48	31.7
High risk group (≥ 118)	140	47	33.6
SYNTAX scores (points)				4.381	0.042
Low risk group (0-22)	330	85	25.8
Intermediate risk group (23-32)	42	17	40.5
High risk group (≥ 33)	14	6	42.9
Treatment				8.123	0.021
Medication group	195	36	18.5
Stent group	156	57	36.5
CABG group	35	15	42.9
Total	386	108	28.0

Hc value: The test statistic for the Kruskal-Wallis test; MACEs: Major adverse cardiovascular events.

Table 3 Major adverse cardiovascular events rate in patients with different GRACE risk scores receiving different treatments, n (%)

GRACE risk scores (points)	n	Medication group		Stent group		CABG group		Overall MACE rate	Hc value	P value
		n	MACE rate	n	MACE rate	n	MACE rate
Low risk group (0-88)	95	65	4 (6.2)	25	7 (28.0)	5	2 (40.0)	13 (13.7)	5.231	0.041
Intermediate risk group (89-117)	151	71	22 (31.0)	66	20 (30.3)	14	6 (42.9)	48 (31.8)	2.742	0.086
High risk group (≥ 118)	140	59	10 (16.9)	65	30 (46.2)	16	7 (43.8)	47 (33.6)	5.381	0.040
Total	386	195	36 (18.5)	156	57 (36.5)	35	15 (42.9)	108 (28.0)	4.412	0.044

CABG: Coronary artery bypass grafting; Hc value: The test statistic for the Kruskal-Wallis test; MACE: Major adverse cardiovascular events.

Table 4 Major adverse cardiovascular events rate in patients with different SYNTAX risk scores receiving different treatments, n (%)

SYNTAX risk scores (points)	n	Medication group		Stent group		CABG group		Overall MACE rate	Hc value	P value
		n	MACE rate	n	MACE rate	n	MACE rate
Low risk group (0-22)	330	185	30 (16.2)	130	46 (35.4)	15	9 (60.0)	85 (25.8)	12.213	0.001
Intermediate risk group (23-32)	42	8	3 (37.5)	22	9 (40.9)	12	5 (41.7)	17 (40.5)	1.984	0.214
High risk group (≥ 33)	14	2	1 (50.0)	4	3 (75.0)	8	2 (25.0)	6 (42.9)	8.432	0.014
Total	386	195	36 (18.5)	156	57 (36.5)	35	15 (42.9)	108 (28.0)	4.412	0.044

CABG: Coronary artery bypass grafting; Hc value: the test statistic for the Kruskal-Wallis test; MACE: major adverse cardiovascular events.