Efficacy of roxadustat in treatment of peritoneal dialysis patients with renal anaemia

Table 1 Clinical indicators evaluated during follow-up

Index	EPO phase	Roxadustat phase
Haemoglobin (g/L)	86.2 ± 14.8	112.4 ± 18.5b
Hb compliance rate (%)	16.10%	67.70%
Ferritin (μg/L)	316 ± 236	243 ± 260
Iron (μmol/L)	12.3 ± 4.4	15.3 ± 4.5
Transferrin (mg/dL)	190 ± 39	233 ± 42b
TSAT (%)	19.2 ± 5.7%	26.5 ± 7.6%a
Folic acid (nmol/L)	19.6 ± 13.7	24.7 ± 15.3
Vitamin B12 (pmol/L)	434 ± 147	627 ± 314
TC (mmol/L)	4.72 ± 1.46	4.23 ± 0.83
LDL-C (mmol/L)	2.81 ± 1.05	2.45 ± 0.90
HDL-C (mmol/L)	0.99 ± 0.36	0.88 ± 0.26
TG (mmol/L)	2.67 ± 2.46	2.3 ± 1.44
CRP (mg/L)	16.1 ± 34.3	10.3 ± 11.8
Potassium (mmol/L)	4.26 ± 1.07	4.26 ± 1.11
Bicarbonate radical (mmol/L)	24.4 ± 4.2	25.0 ± 2.2
Calcium (mmol/L)	2.22 ± 0.18	2.24 ± 0.20
Phosphorus (mmol/L)	2.03 ± 0.49	1.99 ± 0.66
Parathormone (pmol/L)	71.9 ± 62.1	41.5 ± 26.3
Albumin (g/L)	37.2 ± 3.5	36.8 ± 3.9
PAB (ml/dL)	38.7 ± 5.5	33.1 ± 6.5*
Creatinine (μmol/L)	1058 ± 311	1039 ± 217
Urea (mmol/L)	23.26 ± 9.13	20.64 ± 8.18
Cystatin C (mg/L)	6.75 ± 1.39	7.37 ± 1.20
Mean SBP (mmHg)	136.2 ± 10.5	139.2 ± 7.4
Mean DBP (mmHg)	87.2 ± 7.5	88.1 ± 6.9

^aP < 0.05, compared with the same group before treatment.

^bP < 0.001, compared with the control group at the same time.

EPO: Erythropoietin; Hb: Haemoglobin; TSAT: Transferrin saturation; TC: Total cholesterol; TG: Triglyceride; CRP: C-reactive protein; PAB: Prealbumin; SBP: Systolic blood pressure; DBP: Diastolic blood pressure.