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©The Author(s) 2021.
World J Clin Cases. Aug 16, 2021; 9(23): 6717-6724
Published online Aug 16, 2021. doi: 10.12998/wjcc.v9.i23.6717
Published online Aug 16, 2021. doi: 10.12998/wjcc.v9.i23.6717
Table 1 Baseline data comparison between the clarithromycin group and the erythromycin group, n (%)
Baseline data | Clarithromycin group (n = 53) | Erythromycin group (n = 53) | χ2/t | P value |
Gender | 0.641 | 0.423 | ||
Male | 28 (52.83) | 29 (54.72) | ||
Female | 25 (47.17) | 24 (45.28) | ||
School | ||||
Kindergarten | 11 (20.75) | 10 (18.87) | 0.111 | 0.739 |
Primary school | 38 (71.70) | 37 (69.81) | 0.086 | 0.769 |
Junior high school | 4 (7.55) | 6 (11.32) | 0.832 | 0.362 |
Age | 6.74 (1.25) | 6.83 (1.22) | 1.050 | 0.862 |
Table 2 Comparison of the total clinical effectiveness in the clarithromycin group and the erythromycin group, n (%)
Group | Number of cases | Invalid | Effective | Marked effect | Total clinical effectiveness |
Clarithromycin group | 53 | 2 (3.77) | 19 (35.85) | 32 (60.38) | 51 (96.23) |
Erythromycin group | 53 | 13 (24.53) | 22 (41.51) | 18 (33.96) | 40 (75.47) |
χ2 | - | 17.739 | 0.675 | 14.005 | 17.739 |
P value | - | 0.001 | 0.411 | 0.001 | 0.001 |
Table 3 Hospital stay time, drug cost, and antipyretic time of the clarithromycin group vs the erythromycin group (mean ± SD)
Clarithromycin group (n = 53) | Erythromycin group (n = 53) | t | P value | |
Hospital stays (d) | 15.14 ± 2.01) | 20.63 ± 3.15 | 10.696 | 0.001 |
Drug cost (Yuan) | 1654.63 ± 100.21 | 2152.14 ± 163.48 | 18.889 | 0.001 |
Antipyretic time (d) | 2.63 ± 0.57 | 4.06 ± 0.75 | 11.051 | 0.001 |
Table 4 Toxic side effects of the clarithromycin group compared with the erythromycin group, n (%)
Group | Number of cases | Stomach ache | Diarrhea | Nausea | Other | Incidence of side effects |
Clarithromycin group | 53 | 2 (3.77) | 1 (1.89) | 2 (3.77) | 3 (5.66) | 8 (15.09) |
Erythromycin group | 53 | 8 (15.09) | 7 (13.21) | 10 (18.87) | 11 (20.75) | 36 (67.92) |
χ2 | - | 7.502 | 9.179 | 11.357 | 9.934 | 57.479 |
P value | - | 0.006 | 0.002 | 0.001 | 0.002 | 0.001 |
Table 5 Comparison of medication compliance between the clarithromycin group and the erythromycin group, n (%)
Group | Number of cases | Full compliance | Obey | Disobey | Medication compliance |
Clarithromycin group | 53 | 40 (81.13) | 12 (22.64) | 1 (1.89) | 52 (98.11) |
Erythromycin group | 53 | 18 (33.96) | 20 (37.74) | 15 (28.30) | 38 (71.70) |
χ2 | - | 45.537 | 5.409 | 27.211 | 27.211 |
P value | - | 0.001 | 0.020 | 0.001 | 0.001 |
- Citation: Zhang MY, Zhao Y, Liu JF, Liu GP, Zhang RY, Wang LM. Efficacy of different antibiotics in treatment of children with respiratory mycoplasma infection. World J Clin Cases 2021; 9(23): 6717-6724
- URL: https://www.wjgnet.com/2307-8960/full/v9/i23/6717.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v9.i23.6717