Prognostic factors and its predictive value in patients with metastatic spinal cancer

Table 1 Univariate analysis of influential factors for the prognosis of patients with spinal metastatic tumors

Clinical characteristics	n	Survival group, n = 28	Death group, n = 81	χ2 value	P value
Gender				0.981	0.456
Male	68	16	52
Female	41	12	29
Age in yr				34.542	0.001
20 to 39	23	10	13
40 to 59	61	15	46
60 to 89	25	3	22
Comorbidity of metastases from elsewhere				45.890	0.001
Yes	65	7	58
No	44	21	23
Types of primary lesions				2.342	0.108
Lung cancer	27	8	19
Gastric cancer	23	4	19
Thyroid cancer	20	5	15
Breast cancer	19	7	12
Intestinal cancer	13	3	10
Other cancers	7	1	6
Therapies				19.221	0.001
Subtotal resection combined with internal fixation and decompression	60	12	48
Minimally invasive percutaneous spine surgery	49	16	33
Number of spinal tumors				5.762	0.041
1 to 2	47	16	31
≥ 3	62	12	50
Patient attitudes toward tumors				4.093	0.046
Face it positively	29	9	20
Accept it	41	14	27
Deny it	12	2	10
Resist it	27	3	24
Karnofsky performance score				13.674	0.001
10 to 30	6	0	6
30 to 50	25	4	21
50 to 70	54	10	44
70 to 90	24	14	10

Table 2 Frankel spinal cord injury functional classification scale score in patients with spinal metastatic tumors of different outcomes, n (%)

Groups	n	Time points	Frankel spinal cord injury functional classification scale score
			Grade A	Grade B	Grade C	Grade D	Grade E
Survival group	28	Before surgery	0 (0.0)	0 (0.0)	2 (7.1)	5 (17.9)	21 (75.0)
		1 mo after surgery	0 (0.0)	0 (0.0)	0 (0.0)	6 (21.4)	22 (78.6)
Death group	81	Before surgery	0 (0.0)	3 (3.7)a	11 (13.6)a	21 (5.9)a	46 (56.8)a
		1 mo after surgery	15 (18.5)b	14 (17.3)b	8 (9.9)b	23 (28.4)	21 (25.9)b

^aP < 0.05 vs the survival group before the surgery;

^bP < 0.05 vs the survival group at 1 mo after the surgery.

Table 3 Comparison of spinal instability neoplastic score between the survival group and the death group, n (%)

Groups	n	SINS score, points
		1 to 6	7 to 12	13 to 18
Survival group	28	12 (42.8)	13 (46.4)	3 (10.7)
Death group	81	11 (13.6)	61 (75.3)	9 (11.1)
χ2 value		8.125	13.098	0.542
P value		0.015	0.009	0.761

SINS: Spinal instability neoplastic score.

Table 4 Differences in the revised Tokuhashi score between the survival group and the death group, n (%)

Groups	n	Revised Tokuhashi score, points
		0 to 8	9 to 11	12 to 15
Survival group	28	6 (21.4)	10 (35.7)	12 (42.8)
Death group	81	34 (42.0)	36 (44.4)	11 (13.6)
χ2 value		11.153	5.327	16.542
P value		0.001	0.041	0.001