Alport syndrome combined with lupus nephritis in a Chinese family: A case report

Table 1 Laboratory data at presentation

Parameter	Proband	Daughter	Son	Reference range
Height (cm)	177	145	140	—
Weight (kg)	75	38	35	—
Blood routine tests
WBC, 109/L	3.0↓			3.5-9.5
HGB, g/L	91↓			115-150
Platelet count, 109/L	60↓			125-350
RBC, 1012/L	3.3↓			3.8-5.1
Urine routine tests
Specific gravity	1.018	1.020	1.015	1.015-1.030
Urine protein	2+↑	2+↑	3+↑1	5.5-7.5
Urinary occult blood	3+↑	3+↑	3+↑1	Negative
24-h UPE, g/d	2.45↑			0-0.12
Immunology
Complement C3, g/L	0.21↓			0.9-2.1
Anti-ANA antibody	1:320			Negative
Anti-Sm antibody	Positive↑			Negative
Anti-dsDNA antibody	Positive↑			Negative
Serum chemistry				Negative
Albumin, g/L	31.5↓			40-55
Serum creatinine, μmol/L	121↑			45-105
Cystatin-C, mg/L	1.45↑			0-1.16

¹Indicates the abnormal value detected out of the reference range. WBC: White blood cells; HGB: Hemoglobin; RBC: Red blood cells; UPE: Urinary protein excretory.