Alopecia treatment using minimally manipulated human umbilical cord-derived mesenchymal stem cells: Three case reports and review of literature

Table 1 Transplantation of minimally manipulated umbilical cord-derived mesenchymal stem cells into case 1

Treatment number	Date	Concentration of injection solution	Volume of injection solution	Number of lesion sites
1	May 29, 2016	1 × 106 cells/mL	1 mL/lesion site	2 (right, left)
2	June 7, 2016
3	June 22, 2016
4	June 30, 2016
5	July 8, 2016
6	July 20, 2016
7	July 27, 2016
8	August 3, 2016
9	August 16, 2016
10	August 29, 2016
11	September 15, 2016
12	October 11, 2016
13	October 26, 2016
14	November 8, 2016
15	November 22, 2016

Table 2 Transplantation of minimally manipulated umbilical cord-derived mesenchymal stem cells into case 2

Treatment number	Date	Concentration of injection solution	Volume of injection solution	Number of lesion sites
1	March 19, 2018	1 × 106 cells/mL	1 mL/lesion site	1
2	April 12, 2018

Table 3 Transplantation of minimally manipulated umbilical cord-derived mesenchymal stem cells into case 3

Treatment number	Date	Concentration of injection solution	Volume of injection solution
1	February 12, 2014	1 × 106 cells/mL	6 mL
2	February 26, 2014		10 mL
3	March 12, 2014		10 mL
4	March 28, 2014		12 mL
5	April 14, 2014		12 mL
6	June 23, 2014		12 mL
7	July 21, 2014		36 mL
8	August 6, 2014		12 mL
9	September 2, 2014		12 mL
10	September 25, 2014		12 mL
11	October 10, 2014		12 mL
12	November 5, 2014		12 mL
13	January 16, 2015		24 mL
14	February 10, 2015		12 mL

Table 4 The hair density of lesions of case 1

Lesion	No.	Hair density (hairs/cm2)	Mean (hairs/cm2)
Right side	1	169	169.33 ± 1.53
	2	168
	3	171
Left side	1	165	168.00 ± 2.65
	2	169
	3	170

Table 5 The hair density of lesions of case 2

Lesion	No.	Hair density (hairs/cm2)	Mean (hairs/cm2)
Top of scalp	1	163	162.00 ± 2.65
	2	159
	3	164