Successful treatment of infantile hepatitis B with lamivudine: A case report

Table 1 Laboratory test results on admission (December 14, 2015)

Serum marker (unit)	Actual value	Reference range
Alanine aminotransferase (U/L)	106	1-52
Aspartate aminotransferase (U/L)	107	1-40
HBsAg (COI)	685.2	< 1
HBsAb (mIU/mL)	< 2	< 10
HBeAg (COI)	1454.0	< 1
HBeAb (COI)	11.89	> 1
HBcAb (COI)	0.009	> 1
HBcAb-IgM (COI)	2.07	< 1
HBV DNA (IU/mL)	> 1.0 × 109	< 1.0 × 102

COI: Cut-off index; HBcAb: Hepatitis B core antibody; HBcAb-IgM: Immunoglobulin M antibody to hepatitis B core antigen; HBeAb: Hepatitis B “e” antibody; HBeAg: Hepatitis B “e” antigen; HBV: Hepatitis B virus; HBsAb: Hepatitis B surface antibody; HBsAg: Hepatitis B surface antigen.

Table 2 Partial laboratory test results from last reexamination (July 2, 2020)

Serum marker (unit)	Actual value	Reference range
Alanine aminotransferase (U/L)	18	1-52
Aspartate aminotransferase (U/L)	33	1-40
HBsAg (IU/mL)	< 0.03	< 0.05
HBsAb (mIU/mL)	> 1000	0.0-10.00
HBeAg (PEIU/mL)	< 0.01	0.00-0.11
HBeAb (PEIU/mL)	< 0.1	> 1.10
HBcAb (IU/mL)	< 0.1	> 1.10
HBV DNA (IU/mL)	< 30	< 30
White blood cell (109/L)	5.95	4.0-10.0
Neutrophil (109/L)	2.66	2.00-7.00
Red blood cell (1012/L)	4.16	3.50-5.50
Platelet (109/L)	306.0	100.0-300.0

HBcAb: Hepatitis B core antibody; HBeAb: Hepatitis B “e” antibody; HBeAg: Hepatitis B “e” antigen; HBsAg: Hepatitis B surface antigen; HBV: Hepatitis B virus.

Table 3 Blood sampling schedule

Date	Item
December 14, 2015	ALT, HBsAg, HBsAb, HBeAg, HBeAb, HBV DNA
April 1, 2016	ALT
May 3, 2016	HBsAg, HBsAb, HBeAg, HBeAb, HBV DNA
August 11, 2016	ALT, HBsAg, HBsAb, HBeAg, HBeAb, HBV DNA
November 2, 2016	HBsAg, HBsAb, HBeAg, HBeAb
March 22, 2017	HBsAg, HBsAb, HBeAg, HBeAb, HBV DNA
July 20, 2017	ALT, HBsAg, HBsAb, HBeAg, HBeAb
December 11, 2017	ALT, HBsAg, HBsAb, HBeAg, HBeAb, HBV DNA
April 8, 2018	HBsAg, HBsAb, HBeAg, HBeAb
July 31, 2018	HBsAg, HBsAb, HBeAg, HBeAb
January 6, 2019	HBsAg, HBsAb, HBeAg, HBeAb
November 27, 2019	ALT, HBsAg, HBsAb, HBeAg, HBeAb, HBV DNA
July 2, 2020	ALT, HBsAg, HBsAb, HBeAg, HBeAb, HBV DNA

HBeAb: Hepatitis B “e” antibody; HBeAg: Hepatitis B “e” antigen; HBsAg: Hepatitis B surface antigen; HBV: Hepatitis B virus; ALT: Alanine aminotransferase.