Acquired haemophilia in patients with malignant disease: A case report

Table 1 Laboratory values upon admission

		Value	Unit	Normal range
Glucose		5.5	mmol/L	3.6-6.1
Urea	H	8.9	mmol/L	2.8-7.5
Sodium		138	mmol/L	135-145
Potassium		4.6	mmol/L	3.7-4.9
Creatinine	H	149	µmol/L	44-97
eGFR (CDK-EPI)		41	mL/min per 1.73 m2
Bilirubin, total	H	52	µmol/L	< 17
Bilirubin, direct	H	33	µmol/L	< 5
AP	H	10.72	µkat/L	< 2.15
AST	H	1.08	µkat/L	< 0.58
ALT	H	1.68	µkat/L	< 0.74
GGT	H	10.86	µkat/L	< 0.94
Amylase		1.15	µkat/L	< 1.67
Lipase		0.61	µkat/L	< 1.00
LDH	H	5.50	µkat/L	< 4.13
CRP	H	63	mg/L	0-5
Procalcitonin	H	0.31	µg/mL	< 0.24
WBC		9.4	109/L	4.0-10.0
RBC	L	2.04	1012/L	4.50-5.50
Haemoglobin	L	65	g/L	130-170
Haematocrit	L	0.190	1	0.400-0.500
MCV		93.0	fL	83.0-101.0
Platelet count		349	109/L	150-410
Prothrombin time		1.00	1	0.70-1.30
INR		1.00		< 1.30
D-dimer	H	7904	µg/L	< 500

ALT: Alanine transaminase; AP: Alkaline phosphatase; AST: Aspartate transaminase; CRP: C-reactive protein; eGFR: Estimated glomerular filtration rate; GGT: Gamma-glutamyl transferase; H: High; L: Low; LDH: Lactate dehydrogenase; MCV: Mean corpuscular volume; RBC: Red blood cell count; WBC: White blood cell count.

Table 2 Coagulation tests performed during admission

		Value	Unit	Normal range
Prothrombin time		1.00	1	0.70-1.30
INR		1.00		< 1.30
aPTT	H	92	s	25.9-36.6
Fibrinogen		2.67	g/L	1.8-3.5
Thrombin time		15.7	s	14.0-21.0
D-dimer	H	4040	µg/L	< 500
Factor VIII:C	L	0.01	IU/mL	0.50-1.50
Factor VIII antibodies	H	30	BU/mL	0

aPTT: Activated partial thromboplastin time; BU: Bethesda units; H: High; INR: International normalized ratio; L: Low.