Hepatoid adenocarcinoma of the stomach: Thirteen case reports and review of literature

Table 1 Laboratory examination data of 13 patients with hepatoid adenocarcinoma of the stomach

Serial number	Sex	Age	Preoperative AFP (0.89-8.78 ng/mL)	Preoperative CEA (0-5 ng/mL)
1	Male	68		186.31
2	Male	63	43.19	51.28
3	Male	58	3.25	1.08
4	Male	66	> 700	2.56
5	Male	59	5.93	3.02
6	Female	55	1.41	2.54
7	Male	60	779.91	3.65
8	Female	85	1085.75	26.73
9	Male	70	1.79	2.45
10	Male	74		41.34
11	Male	71	39.87	21.47
12	Female	66	8.8	262.67
13	Male	64	508.69	12.81

AFP: Alpha-fetoprotein; CEA: Carcinogenic embryonic antigen.

Table 2 Imaging examination data of 13 patients with hepatoid adenocarcinoma of the stomach

Serial number	Tumour location	Gastric wall thickening	Enlarged lymph nodes	Liver metastases
1	Gastric sinus	Yes	No	No
2	Cardia	Yes	Yes	No
3	Gastric body	Yes	Yes	No
4	Gastric body	No	No	No
5	Gastric sinus	Yes	Yes	No
6	Gastric sinus	Yes	No	No
7	Gastric sinus	Yes	Yes	No
8	Gastric sinus	No	No	No
9	Gastric sinus	Yes	Yes	No
10	Gastric sinus	Yes	Yes	No
11	Gastric sinus	Yes	Yes	No
12	Gastric body	Yes	Yes	No
13	Cardia	Yes	No	No

Table 3 Postoperative and follow-up data of 13 patients with hepatoid adenocarcinoma of the stomach

Serial number	TNM	Clinicopathologic stage	Lymph node	AFP	Hepatocyte	Adjuvant chemotherapy	Follow-up	Progression	Progression-free survival (mo)
1	T4aN3aM0	IIIB	(8/13)	+	-	Yes	Survival	No	56
2	T4aN2M0	IIIA	(5/15)	+	+	Yes	Death	Yes	28
3	T2N0M0	IB	(0/35)	-	+	Yes	Survival	No	56
4	T4N0M0	IIB	(0/14)	+	Unknown	Yes	Death	Yes	27
5	T4N1M0	IIIB	(6/22)	+	+	Yes	Lost	No	Unknown
6	T4N0M0	IIB	(0/18)	-	+	Yes	Survival	Yes	56
7	T4N3bM1	IV	(18/27)	+	+	Yes	Death	Yes	32
8	T4aN3aM0	IIIB	(7/18)	+	Unknown	No	Death	Yes	6
9	T4N3bM0	IIIC	(15/18)	-	+	Yes	Survival	Yes	23
10	T4bN2M0	IIIB	(7/23)	+	+	No	Death	Yes	1
11	T4bN1M0	IIIB	(3/17)	-	Unknown	Yes	Lost	Unknown	Unknown
12	T3N1M0	IIB	(3/21)	+	Unknown	No	Lost	Unknown	Unknown
13	T3N3bM0	IIIC	(16/19)	+	+	Yes	Survival	Yes	11

+ means positive; – means negative; AFP: Alpha-fetoprotein.