High serum lactate dehydrogenase and dyspnea: Positive predictors of adverse outcome in critical COVID-19 patients in Yichang

Table 1 Clinical characteristics of patients with critical coronavirus disease 2019

Clinical features	Groups		P value
	Non-survivors (n = 17)	Survivors (n = 30)
Age (yr)	69.0 (63.5-78.0)	67.0 (55.5-77.0)	0.595
Male (%)	11 (64.7)	15 (50.0)	0.33
Days of hospitalization (d)	14.0 (8.0-24.5)	33.0 (16.8-38.3)	0.001b
Disease duration (d)1	23.0 (15.5-29.5)	38.0 (24.5-45.3)	0.005b
Duration of viral shedding (d)	8.0 (6.0-18.0)	11.0 (8.8-20.5)	0.118
Days from illness onset to hospital admission (d)	5.0 (2.0-10.0)	5.0 (3.75-7.25)	0.689
Duration of alveolitis phase (d)	12.0 (8.0-17.5)	17.0 (13.8-21.0)	0.020a
Duration of fibrosis phase (d)	10.0 (5.5-15.5)	19.0 (10.0-26.0)	0.016a
Complication of COPD (%)	3 (17.6)	3 (10.0)	0.764
Complication of hypertension (%)	10 (58.8)	11 (36.7)	0.142
Complication of coronary heart disease (%)	7 (41.2)	6 (20.0)	0.222
Complication of cerebrovascular disease (%)	3 (17.6)	7 (23.3)	0.931
Complication of diabetes (%)	5 (29.4)	7 (23.3)	0.912
Complication of renal dysfunction (%)	2 (11.8)	5 (16.7)	0.978
Complication of malignant tumors (%)	2 (11.8)	3 (10.0)	1.000
Other complications (%)2	7 (41.2)	6 (20.0)	0.222
Number of complications	2.0 (1.5-3.5)	1.5 (0.0-3.0)	0.139
Fever (%) (temperature ≥ 37.3°C)	13 (76.5)	26 (86.7)	0.624
Cough (%)	7 (41.2)	20 (66.7)	0.089
Dyspnea (%)	9 (52.9)	4 (13.3)	0.010a
Fatigue (%)	5 (29.4)	4 (13.3)	0.337
Other symptoms (%)3	5 (29.4)	4 (13.3)	0.337

¹Time from illness onset to death or discharge, days.

²Thyroid dysfunction, prostatic hyperplasia, schizophrenia.

³Arthralgia, sputum, dizziness, nausea, chest pain, diarrhea.

^aP < 0.05; ^bP < 0.01. COPD: Chronic obstructive pulmonary disease.