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Copyright ©The Author(s) 2020.
World J Clin Cases. Nov 26, 2020; 8(22): 5501-5512
Published online Nov 26, 2020. doi: 10.12998/wjcc.v8.i22.5501
Table 1 Imaging manifestations of coronavirus disease-2019 on chest computed tomography
Stage
Chest CT findings
Pathology
Early stage (0-4 d after symptom onset)Ground-glass opacity and reticular pattern (44%-93%), consolidation (7%-17%)Interstitial edema and thickening as the result of inflammatory infiltration
Advanced stage (5-8 d after symptom onset)GGO and reticular pattern (81%-88%), “crazy-paving” pattern, consolidation in unilateral or bilateral lungs (15%-55%) Edematous thickening of interstitial structures and interlobular septa; partial collapse of alveolar space; viscous and fibrinous exudate in alveolar space with hyaline membrane formation
Severe stage (9-13 d after symptom onset)GGO (33%-57%), diffuse patchy consolidation (33%-60%) of both lungs, vascular enlargement sign, bronchial wall thickening and bronchiectasis; white lungAlveolar proteinaceous and viscous exudate mixed with cellular debris, blood products and fibroblast plugs; injury of the endothelial cells of the small blood vessels with consequent thrombosis; bronchiolar dilatation and wall thickening
Absorption stage (14 d later after symptom onset)The density of the consolidation was gradually reduced with a decrease in the volume of lesion opacities; some fibrous streaks and reticular shadows may persistInfiltrative and exudative lesions were absorbed with some remaining fibrous proliferation and focal fibrosis