Observational Study
Copyright ©The Author(s) 2020.
World J Clin Cases. Jan 26, 2020; 8(2): 276-283
Published online Jan 26, 2020. doi: 10.12998/wjcc.v8.i2.276
Table 1 Patient demographics and laboratory results of hospitalised paediatric oncology patients with diarrhoea at Bangabandhu Sheikh Mujib Medical University hospital, n (%)
ParticularsStudy 11Study 22
Male:Female32:1947:19
Age in mo, range (mean)13-180 (70.8)11-216 (73.2)
Age group
≤ 60 mo32 (55.2)41 (58.6)
61-120 mo16 (27.6)15 (21.4)
> 120 mo10 (17.2)14 (20)
Diagnosis
ALL37 (63.8)40 (57.1)
NHL17 (29.4)10 (14.3)
AML4 (7.9)7 (10)
Others1 (1.4)
Solid tumours12 (17.1)
Phase of treatment
Induction37 (63.8)43 (61.4)
Consolidation14 (24.1)10 (14.3)
Maintenance6 (10.3)12 (17.1)
Not applicable1 (1.7)5 (7.1)
ANC category
< 500/mm347 (81)42 (60)
≥ 500/mm311 (19)28 (40)
Number of bowel motions/d
≥ 1029 (50)10 (14.2)
6-919 (32.8)40 (57.1)
≤ 510 (17.2)20 (28.6)
Pathogens detected in stool samples
Giardia lamblia37 (68.5)21 (1.4)
Entamoeba histolytica7 (13)27 (10)
Cryptosporidium3 (5.6)23 (4.3)
Clostridium difficile13 (22.4)2 (5.1)2
Campylobacter jejuni2 (3.4)1 (1.4)
Salmonella spp1 (1.7)1 (1.4)
Shigella sonnei0 (0)1 (1.4)
Vibrio cholerae0 (0)1 (1.4)
Table 2 Summary of paediatric oncology patients with diarrhoea from whose stool samples Cryptosporidium was detected
PatientsAge in yrGenderPrimary diagnosisPhase of treatmentPreceding hospital stay in d1Frequency of bowel motions/dFeverMucositisStool microscopyANC
Study 1
Patient 14.5MaleNHLInduction1516PresentPresent11-20 pus cells per HPF150
Patient 23.5MaleALLMaintenance06-9PresentAbsent> 50 pus cells per HPF20
Patient 36MaleALLMaintenance03PresentAbsent> 10 per HPF180
Study 2
Patient 14MaleRMSInduction7> 10AbsentAbsentNormal790
Patient 25FemalePNETInduction06-9PresentPresentPus cells20
Patient 32.5MaleALLInduction226-9PresentAbsentNormal40