Hand-assisted laparoscopic splenectomy is a useful surgical treatment method for patients with excessive splenomegaly: A meta-analysis

Table 1 Description of included studies

Author	HALS/LS	Splenic weight	M/F	MBI	Maximum diameter (cm)	Malignant	Blood loss (mL)	Transfusion	Operative time (min)	Conversion	Complication	Total score	Hospital stay length (d)	Diet (d)	Mortality	Splenomegaly
Ailawadi et al[20]	22/19	1.3 ± 1013/0.87 ± 0.571	27/14	-	-	16/11	492 ± 630/846 ± 10841	-	161 ± 45/212 ± 611	3/7	74/6	6	3.6 ± 1.7/4.5 ± 3.71	2.3 ± 0.7/2.3 ± 0.71	0/3	Y
Kercher et al[21]	7/49	-	-	-	-	-	-	0/2	283 ± 107/210 ± 207	0/0	0/3	6	-		0/0	Y
Rosen et al[22]	14/31	1.516/1.031	29/16	25/28	-	9/16	602/376	-	177/186	1/7	5/6	6	5.4/4.2		0/0	Y
Targarona et al[11]	20/36	1.753 ± 1.124/1.425 ± 0.844	34/22	-	26 ± 8/25 ± 5	-	-	7/14	135 ± 52/177 ± 52	1/7	2/13	8	4 ± 1.2/6.3 ± 3.3	-	0/0	Y
Smith et al[23]	4/3	1.425/0.638	-	-	-	-	220/75	3/0	88.4/82	-	2/0	6	5/3	-	-	N
Wang et al[24]	20/16	1.346 ± 0.735/1.185 ± 0.546	19/17	-	27 ± 7/24 ± 5	-	86 ± 45/138 ± 80	-	141 ± 64/195 ± 71	0/4	0/2	8	7.4 ± 1.6/5.3 ± 3.8	-	-	Y
Reso et al[25]	10/9	-	-	-	-	-	-	-	-	0/0	-	7	-	-	2/3	Y
Pietrabissa et al[26]	43/42	2.46 ± 1.5/1.15 ± 0.69	55/29	24.1 ± 6.6/24 ± 4.6		-	-	-	184 ± 22/176 ± 18	1/1	29/13	7	5 ± 2/4 ± 3	-	1/0	Y
Altaf et al[27]	23/80	2.166 ± 1.446/0.209 ± 0.166	49/54	26.9 ± 4.8/28.7 ± 6.8	-	20/16	351 ± 716/84 ± 151	4/8	172 ± 54/125 ± 49	1/0	8/21	7	6.9 ± 7/3.5 ± 5	3.5 ± 2.7/1.8 ± 3	-	N
Wang et al[14]	19/20	-	16/23	-	28 ± 7/24 ± 5	-	92 ± 65/169 ± 136	1/4	124 ± 42/195 ± 43	0/0	4/9	8	7.2 ± 2.8/8.5 ± 2.3	1 ± 0.1/1.1 ± 0.3	-	Y
Wang et al[28]	41/45	-	45/41	21.9 ± 2.3/21.1 ± 2.1	27.4 ± 7.6/24.7 ± 5.1	-	81 ± 57/149 ± 84	3/9	136 ± 41/179 ± 54	0/2	17/22	8	8.5 ± 2.9/8.8 ± 3.5	2.1 ± 0.9/2.3 ± 0.9	1/0	Y
Ando et al[29]	6/10	0.583 ± 0.253/0.457 ± 0.225	-	-	-	0	531 ± 390/342 ± 513	-	341 ± 94/224 ± 56	-	4/1	7	19.8 ± 8.7/14.6 ± 3.5	-	-	-
Li et al[30]	31/27	-	42/16	-	-	0	238 ± 89/287 ± 115	-	201 ± 41/241 ± 35	0/1	-	7	10.2 ± 3.1/9.8 ± 2.9	2.4 ± 1.3/2.2 ± 1.2	0/0	-
Yu et al[31]	16/14	-	17/13	-	-	0	250 ± 53/370 ± 45	-	270 ± 21/350 ± 19	0/0	0/1	7	12.2 ± 1/11.8 ± 1.1	5.7 ± 0.6/5.4 ± 0.8	0/0	-
Akahoshi et al[32]	10/9	0.680 ± 0.233/0.526 ± 0.321	11/8	-	-	0	250 ± 210/981 ± 821	-	245 ± 51/336 ± 67	0/4	3/4	8	6.5 ± 4.2/10.2 ± 5.5	-	0/0	-
Li et al[33]	29/29	-	29/29	-	-	0	335 ± 12/413 ± 12	-	183 ± 8/205 ± 8	-	3/8	8	-	2.7 ± 0.4/3.1 ± 0.5	0/0	-

¹The mean and SD were estimated by median and a range; total score was calculated by adding up the points awarded in each item using the Newcastle-Ottawa Scale.