Pneumococcal infection transmission between family members with congenital asplenia: A case report

Table 1 Laboratory data of Patient 1 upon admission

Parameter	Recorded value	Standard value
White blood cell count	6400 /µL	3590-9640 /µL
Neutrophils	90.2%	41.2%-74.7%
Lymphocytes	8.4%	21.2%-51.0%
Hemoglobin	16.1 g/dL	13.2-17.2 g/dL
Hematocrit	47.3%	40.4%-51.1%
Platelets	3.4 × 104 /µL	(14.8-33.9) × 104 /µL
C-reactive protein	18.2 mg/dL	≤ 0.30 mg/dL
Total protein	5.5 g/dL	6.7-8.3 g/dL
Albumin	2.9 g/dL	3.9-4.9 g/dL
Aspartate aminotransferase	232 U/L	13-33 U/L
Alanine aminotransferase	154 U/L	6-30 U/L
Lactate dehydrogenase	700 U/L	119-229 U/L
Creatine phosphokinase	356 U/L	62-287 U/L
Blood nitrogen urea	35 mg/dL	8-22 mg/dL
Creatinine	4.72 mg/dL	0.60-1.10 mg/dL
Sodium	136 mEq/L	138-146 mEq/L
Potassium	4.4 mEq/L	3.6-4.9 mEq/L
Glucose	118 mg/dL	60-160 mg/dL
Hemoglobin A1c	6.7%	4.6%-6.2%
Prothrombin time	24.8 s	9.4-12.5 s
Activated partial thromboplastin time	97.8 s	25.1-36.5 s
Fibrinogen	131 mg/dL	155-415 mg/dL
Fibrin/Fibrinogen degradation products	68.6 µg/mL	0-4.9 µg/mL

Table 2 Laboratory data of Patient 2 upon admission

Parameter	Recorded value	Standard value
White blood cell count	2260 /µL	3040-8540 /µL
Neutrophils	61.1%	38.3%-71.1%
Lymphocytes	37.5%	21.3%-50.2%
Hemoglobin	10.9 g/dL	10.8-14.9 g/dL
Hematocrit	32.8%	35.6%-45.4%
Platelets	15.6 × 104/µL	(15.0-36.1) × 104/µL
C-reactive protein	0.34 mg/dL	≤ 0.30 mg/dL
Total protein	6.5 g/dL	6.7-8.3 g/dL
Albumin	3.9 g/dL	3.9-4.9 g/dL
Aspartate aminotransferase	23 U/L	13-33 U/L
Alanine aminotransferase	11 U/L	6-27 U/L
Lactate dehydrogenase	276 U/L	119-229 U/L
Creatine phosphokinase	200 U/L	45-163 U/L
Blood nitrogen urea	20 mg/dL	8-22 mg/dL
Creatinine	1.32 mg/dL	0.40-0.70 mg/dL
Sodium	144 mEq/L	138-146 mEq/L
Potassium	3.4 mEq/L	3.6-4.9 mEq/L
Glucose	191 mg/dL	60-160 mg/dL
Hemoglobin A1c	6.8%	4.6%-6.2%
Prothrombin time	12.8 s	9.4-12.5 s
Activated partial thromboplastin time	22.1 s	25.1-36.5 s
Fibrinogen	131 mg/dL	155-415 mg/dL
Fibrin/Fibrinogen degradation products	24.6 µg/mL	0-4.9µg/mL

Table 3 Results of antibiotic sensitivity testing (g/mL)

Strain	PCG	ABPC	CTRX	CFPM	CCL	MEPM	CAM	AZM	CLDM	VCM	LVFX
Patient 1	≤ 0.06	≤ 0.12	≤ 0.06	≤ 0.06	≤ 0.5	≤ 0.015	1	> 4	0.12	0.25	1
Patient 2	≤ 0.06	≤ 0.12	≤ 0.06	≤ 0.06	≤ 0.5	≤ 0.015	1	> 4	0.5	0.25	1

ABPC: Ampicillin; CTRX: Ceftriaxone; CFPM: Cefepime; MEPM: Meropenem; AZM: Azithromycin; LVFX: Levofloxacin.