Characteristics of clear cell renal cell carcinoma metastases to the thyroid gland: A systematic review

Table 1 Characteristics of patients and different variables in the study

Characteristics of patients and different variables collected
Age (yr)	mean ± SD
Male	64 ± 10
Female	64 ± 11
Sex	Percentage (Number of patients)
Male	46.3% (68)
Female	52.4% (75)
Initial CCRCC Stage
Stage I CCRCC	30.6% (19)
Stage II CCRCC	29% (18)
Stage III CCRCC	32.3% (20)
Stage IV CCRCC	8.1% (5)
Lag time (years) from initial diagnosis of CCRCC	8.7 ± 6.35 mean ± SD
Size (cm)
Male	4.87 ± 2.55
Female	3.84 ± 1.65
Symptoms
Asymptomatic	21.8% (32)
Painless mass	32.7% (48)
Symptomatic	10.9% (16)
Internal Jugular Thrombus	6.8% (10)
Diagnostics
US	41.2% (35)
CT	20% (17)
PET Scan	15.3% (13)
FNA
diagnostic	29.4% (25)
Non-diagnostic	47.1% (40)
Surgery
Total thyroidectomy	49.0% (72)
Subtotal thyroidectomy	31.3% (46)
Follow up period after the surgery (mo)	26.5 ± 24

Numbers represent mean ± SD or percentage and number of patients. CCRCC: Clear cell renal cell carcinoma; US: Ultrasound; CT: Computed tomography; PET Scan: Positron emission tomography scan; FNA: Fine needle aspiration.

Table 2 Number of metastatic sites from clear cell renal cell carcinoma other than the thyroid gland in the studied population

	Number	Percent
Pancreas	13	16.3
Neck	14	17.5
Liver	6	7.5
Adrenal	7	8.8
Others1	14	17.5
Lung	25	31.3

Percentages of clear cell renal cell carcinoma metastases in different sites other than the thyroid.

¹including metastases in the bones, lymph nodes, exocrine glands, esophagus, intestine, subcutaneous, skeletal muscles.